Exam 2: Vasodilators

Question 1

if vessel 2 has a 2x larger radius than vessel, what is the resistance and flow of vessel 2?

Answer 1

1/16th of vessel 1, flow: 16x vessel 1

Question 2

2 functions of veins

Answer 2

conduct blood back to the heart, reservoir for blood volume 70%

Question 3

increased- venous constriction

Answer 3

increased venous return, increase EDV, increased stretch, increase constraction, etc

Question 4

decreased - venodilation

Answer 4

increased capacitiance, decreased VR, CO, SV, EDV etc

Question 5

classic angina is caused by ___ and can be relieved by ___, unstable is caused by ___ and is an ___, variant is caused by ___ and is ___

Answer 5

plaque, rest, plaque, emergency, hyperreactive vessels and rare

Question 6

we treat variant with ___ or ____

Answer 6

nitrates or CCB

Question 7

we can relax vascular tone by ___ calcium influx and prevent depolarization by ___ efflux

Answer 7

blocking, potassium

Question 8

drug of choice for angina and what vessels do they work oin

Answer 8

nitrates, veins

Question 9

good for nitrates, bad, and ugly

Answer 9

increased Venous Cap., decreased preload and CO. BAD: headache, UGly: reflex tachy

Question 10

long term exposure causes what?

Answer 10

tolerance

Question 11

nitrates activate ___, increase ___ causing ____

Answer 11

guanylyl cyclase, cGMP, relaxation

Question 12

CCB are used to treat what (2)

Answer 12

HTN, angina

Question 13

should not use ___ for heart failure

Answer 13

CCB

Question 14

contraindicated vasodilators

Answer 14

hydralazine, sdoium nitro, fenoldepam

Question 15

most effective treatment for variant angina

Answer 15

CCB

Question 16

beta blockers ___ oxygen demand

Answer 16

decrease