Exam 2: Adrenergic Antagonists

Question 1

reversible antagonists

Answer 1

phentolamine, tolazoline, prazosin, labetalol

Question 2

irreversible antagonists

Answer 2

phenoxybenzamine

Question 3

non-selective alpha antagonists are used to treat ____

Answer 3

pheochromocytoma

Question 4

alpha receptors primarily on ___ muscle

Answer 4

smooth

Question 5

phentolamine is a ___ antagonists for alpha, it causes a ____ in vasc. resistance, minor ___ stimulation, and is used to treat pheochromocytoma, along with male ___

Answer 5

competitive, reduction, cardiac, ED

Question 6

phenoxybenzamine treats pheochromo.., and inhibits ___ reuptake, and it lasts for ___

Answer 6

NE, days

Question 7

prazosin treats ___ and ___, its highly selective for ___ so there’s no tachycardia occurring

Answer 7

HTN and BPH, alpha 1, some alpha 2

Question 8

beta blokcing agents work on the __ and treat ___

Answer 8

heart, anxiety

Question 9

Beta blocking agents have major

Answer 9

1st pass metabolism

Question 10

inotropic means ___, chrono means ___,

Answer 10

force/strength, rate of contraction

Question 11

beta blockers are ___ inotropes and chronotropes

Answer 11

negative

Question 12

respiratory effects: increased airway ___, eye: decreased ___, metabolism: ____ lipolysis

Answer 12

resistance, IOP, inhibit

Question 13

propanolol works on ____, metoprolol works mainly on ___, nebivolol works on ___, nadolol is ____, labetalol is racemic and can work on __ and __

Answer 13

beta 1 and beta 2, beta 1, b1, nonselective, alpha 1 and beta

Question 14

esmolol is very short acting, it can be used to treat intra op ___, its __ selective

Answer 14

tachycardia, beta1

Question 15

all other drugs are compared to ___

Answer 15

propanolol

Question 16

adverse effects of propanolol

Answer 16

brady, rash, sedation, worsening asthma