Exam 2 - Supportive Care

Question 1

highly emetogenic: regimen A

Answer 1

NK-1 antagonist (i.e. aprepitant)
Dexamethasone
5-HT3 antagonist (i.e. ondansetron)
Olanzapine

Question 2

highly emetogenic: regimen B

Answer 2

Olanzapine
Dexamethasone
5-HT3 antagonist (i.e. ondansetron)

Question 3

highly emetogenic: regimen C

Answer 3

NK-1 antagonist (i.e. aprepitant)
Dexamethasone
5-HT3 antagonist (i.e. ondansetron)

Question 4

moderately emetogenic: regimen A

Answer 4

dexamethasone
5-HT3 antagonist (ondansetron)

Question 5

moderately emetogenic: regimen B

Answer 5

olanzapine
palonosetron
dexamethasone

Question 6

moderately emetogenic: regimen C

Question 7

low emetogenic regimens

Answer 7

ONLY 1 NEEDED - Pick any of the following:
1. Dexamethasone
2. Metoclopramide
3. Prochlorperazine
4. 5-HT3 antagonist

Question 8

5-HT3 antagonists: common toxicities

Answer 8

headache, EKG changes (at max doses), constipation

Question 9

corticosteroids: common toxicities

Answer 9

insomnia, hyperglycemia, increased appetite

Question 10

highly emetogenic chemotherapy agents

Answer 10

-doxorubicin
-cyclophosphamide
-cisplatin + carboplatin

Question 11

Anti-emetics are most effective when given as _____________

Answer 11

prophylaxis