Exam #2 Chapter 5 Flashcards
-study that deals with the structure, function, and disorders of the integumentary system
dermatology
-also known as cutaneous membrane, covers the external surface of the body and largest organ of the body
skin
- superficial, thinner portion, composed of keratinized stratified epithelial tissue
- avascular
epidermis
- the _____ has 4 types of cells:
- kerainocytes, melanocytes, intraepidermal macrophages and tactile epithelial cells
epidermis
-the skin consist of two layers the _____ and ____
epidermis and dermis
-90% of the cells, produce keratrin and lamellar granules
keratinocytes
- tough, fibrous protein that helps protect the skin and underlying tissue
- protects against physical damage, heat, microbes
keratin
- produce 8% of cells in epidermis, which develop from ectoderm of a developing embryo and produce the pigment melanin
- hemoglobin in RBC’s
- carotene-vitamin A precursor
melanocytes
- a yellow-red or brown-black pigment that contributes to skin color and absorbs damaging UV light
- located in epidermis in melanocytes
melanin
- arise from red bone marrow and migrate to epidermis, function is for immune response
- also called Langerhans cells
intraepidermal macrophages
- located in the deepest layer of the epidermis, contain flattened process of neurons called tactile disc, detect touch sensation
tactile epithelial cells (merkel cells)
- part of stratum granulosum in epidermis, lipid rich secretion
- function is waterproofing the skin
lamellar graules
-mealnin, keratin, and hemoglobin produces ____
skin color
- deepest layer of epidermis
- single row of cuboidal or columnar cells
- stem cells: actively dividing
- location of melanocytes and tactile epithelial cells
stratum basale
- 8 to 10 layers of keratinocytes in epidermis
- have spines of keratin that insert into desmosomes that gives strength and flexibilty
- superficial to stratum basale
stratum spinosum
- 3 to 5 layers of cells undergoing apoptosis (cell death) in epidermis
- keratin not being produced but stands out as cell dies
- release of lamellar granules to SG, SL, and SC
stratum granulosum
- only present in layers of thick skin such as fingerprints, palms, soles of feet
- 4 to 6 layers of flattened dead cells and thickened plasma membrane, in vepidermis
- extra layer of protection
stratum lucidum
- average 25 to 30 layers of dead keratinocytes, in epidermis
- basically membrane encloses packages of keratin
- layered in complex, wavy folds of protection
stratum corneum
- the deeper, thicker dense irregular connective tissue portion of the skin
- vasular, skin bleeds if cuts
- resist stress and structural support
dermis
- deep to dermis but not part of skin
- consist of areolar and adipose tissue, serves as a storage for fat
subcutaneous layer