Exam 2: Ch 5 Nernst and Goldman Flashcards
Nernst equation states that the equilibrium potential depends on
absolute temp (K)
charge on permeant ion
ratio of the ionic concentration on the two sides of the membrane
nernst equation
Esubx = RT/zF ln (X1/X2)
reduced Nernst equation at 18 celcius
Esubx = .058/z log (X1/X2)
diffusion of a single ion species down its concentration gradient unaccompanied by its counterion can set up…
an electric potential difference between the two sides of the semipermable membrane
at equilibrium, the emf across the membrane is equal to the equilibrium potential
membrane potential equation
Vm = Vin - Vout
is extracellular/intracellular ion [ ]s on top or bottom of nernst?
extracellular in numerator
intracellular in denominator
what is the Goldman equation used for
calculating the steady-state potential for multiple ions
nernst equation gives the equilibrium potential for one ion, but in reality the plasma membrane is permeable to several…
ionic species at a time, which may be asymmetrically distributed
dynamic steady state
in biological systems where exchanges of matter and energy occur continuously across a system