Exam 1- Immunity and Immune disorders M3 Flashcards
what is the diffrence between innate and acquired immunity/
- innate immunity you are born with
- acquired immunity is immunity you get over time
what is an example of innate immunity?
getting immunity from your mother when you are born
what is an example of acquired immunity?
vaccines
what is humoral immunity?
IgG, IgE, IgM
produces antigen specific anitbodies and is lead by b-cells
what is cell mediated immunity?
T-cells, Macrophages
depends on the antibodies for adaptive immune functions
what are the four methods of acquiring immunity?
NA, NP, AA, AP
- natural active
- natural passive
- artficial active
- artifcial passive
what is natural active immunity?
acquired after recovering from infectious disease
what is natural passive immunity?
caused by the neonate and other relationships from IgG antibodies
what is an artificial active immunity?
vaccination
what is artficial passive immunity?
immunotherapy
which immunoglobulin is involved in allergic reactions?
IgE
What are the 4 types of hypersensitivity reactions
- Type I (Anaphylactic Reactions)
- Type 2 (Cytotoxic Reactions)
- Type 3 (Immune Complex Reactions)
- Type 4 (Cell-Mediated or Delayed-type Reactions)
what type of hypersensitive reaction is anaphylaxis?
type 1
what type of hypersensitive reaction is cytotoxic?
type 2
what type of hypersensitive reaction is immune complex?
type 3
what type of hypersensitive reaction is cell mediated?
type 4
what is the etiology/patho of AIDS
- a kind of virus that replicates and uses a single RNA strand and binds to the T helper cell and kills the T- helper
what cells are required for almost all adaptive immune responses?
helper T cells
what are clinical manifestations and complication of Lupus?
CM- F, WL, MOSF
C- SD, A, ESRD, IC, AX, D, PL, O
CM- fever, weight loss, major organ system failure
complications- skin damage, alopecia, increased risk of conornary artery diases, end stage renal diasese, visual changes, anxiety, depression, preg loss, osteoprosis
what can cause inflammation?
- heat
- radiation
- trauma
- chemicals
- allergens
- autoimmune reaction
what is exudate made of intially?
serous fluid
what is exudate made of later on?
plasma protien Albumin
what causes redness, heat, and swelling during inflammation?
increased capillary permability/ vasodilation
what are the local manifestations of inflammation?
redness, heat, pain, swelling, and loss of function
what are systemic manifestation of inflammation?
- increased WBC count
- fatigue
- nausea
- anorexia
- increased RR, pulse
- fever
what do cytokines trigger?
onset of fever by initiate a metabolic changes in temperature
