EX4: SOLUBILITY OF ORGANIC COMPOUNDS Flashcards
a physicochemical property that refers to the ABILITY OF A GIVEN SOLUTE TO BE DISSOLVED in a given amount of solvent
SOLUBILITY
a SUBSTANCE DISSOLVED to create a solution
SOLUTE
ilang phases meron ang SOLUTE
1
kapag hindi nadissolve agad - 2phases
dissolving medium
SOLVENT
LIQUID MIXTURE composed of the solute uniformly dissolved in the solvent
SOLUTION
the PROCESS of dissolving
DISSOLUTION
ilang phases ang SUSPENSION
2 phases
LADME
LIBERATION
ABSORPTION
DISTRIBUTION
METABOLISM
EXCRETION
between SOLID & LIQUID
SOLUBILITY
a solution with the MAXIMUM amount of solute dissolved in the given solvent results in a
SATURATED SOLN
a solution that CONTAINS MORE AMOUNT OF SOLUTE than the solvent results in a
SUPERSATURATED SOLN
ilang phases meron sa SUPERSATURATED SOLN
2 PHASES
a solution that contains LESS AMOUNT OF SOLUTE than the solvent results in
UNSATURATED SOLN
certain substances exhibit solubility property wherein they MIX IN ALL PROPORTIONS, forming a HOMOGENOUS MIXTURE, this property is termed as
MISCIBILITY
between TWO LIQUIDS
MISCIBILITY
kung ano mas marami
SOLVENT
mas stable
SUSPENSION
less stable
SOLUTION
the SOLUBILITY IS CONTROLLED by the energy balance of ____________ between solute-solute, solute-solvent and solvent-solvent molecules
INTERMOLECULAR FORCES OF ATTRACTION
ANO YUNG RULE
LIKE DISSOLVES LIKE
POLAR MOLECULES
dipole-dipole interaction
electronegative atoms / ionic bonding / hydrogen bonding
NON POLAR MOLECULES
VAN DER WAALS dispersion forces
weak / oils, fats, lipids / hydrocarbons
the polarity of a compound depends on the _______________ and the _______________
POLARITIES OF THE INDIVIDUAL BONDS and SHAPE OF THE MOLECULE
the ________of a compound depends on the polarities of the individual bonds and the shape of the molecule
POLARITY
evaluating these factors are quite complicated because of the ____________________ (POLARITY)
COMPLEXITIES OF THE MOLECULES THEMSELVES
all HYDROCARBONS are
NON-POLAR
Compounds with electronegative element (O and N) are generally
POLAR
the degree of _____varies from slightly polar to highly polar.
POLARITY
the degree of polarity varies from ____________________.
SLIGHTLY POLAR TO HIGHLY POLAR
The presence of _______DOES NOT ALTER the POLARITY of the compound
HALOGEN
kapag may halogen, ang polarity ay
SLIGHTLY POLAR
Adding more _______ to the chain makes the compound MORE NON-POLAR
CARBON
Adding MORE CARBON to the chain makes the compound _______
MORE NON-POLAR
_____________ MAKES IT POSSIBLE for the solute TO BE DISSOLVED in the solvent.
HYDROGEN BONDING
Hydrogen bonding makes it possible for the solute __________ in the solvent.
TO BE DISSOLVED
the STRONG ATTRACTION between _______________ makes it possible for the former to be highly soluble to the latter
IONS AND HIGHLY POLAR WATER
the STRONG ATTRACTION between ions and highly polar water molecules makes it possible for the ions to be ___________ to the water
HIGHLY SOLUBLE
acid-base reaction
neutralization reaction
the _________ are COMMONLY EMPLOYED among organic drugs that are poorly soluble in water, thereby ENHANCING ITS ABSORPTION properties
WATER-SOLUBLE SALTS
the WATER-SOLUBLE SALTS are COMMONLY EMPLOYED among organic drugs that are ______ in water, thereby ENHANCING ITS ABSORPTION properties
POORLY SOLUBLE
the WATER-SOLUBLE SALTS are COMMONLY EMPLOYED among organic drugs that are POORLY SOLUBLE in water, thereby ___________ properties
ENHANCING ITS ABSORPTION
APAP
ACETAMINOPHEN
Acetaminophen is also known as
PARACETAMOL
81mg of ASPIRIN
ANTI-COAGULANT
365mg of ASPIRIN
ANALGESIC
ASPIRIN is also known as
ACETYL SALICYLIC ACID
for acne / KERATOLYTIC AGENT
SALICYLIC ACID
anti-bacterial / for burn wounds
SULFADIAZINE
CARBOLIC ACID
PHENOL
CARCINOGENIC
CHLOROFORM