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Oral Histology > Ex 2- Periodontium 1- Development > Flashcards

Ex 2- Periodontium 1- Development Flashcards

1
Q

What structures does the periodontium include?

A 
cementum
PDL
bony socket
gingival facing tooth:
--junctional epithelium
--sulcular epithelium
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2
Q

______ is a calcified material that covers the root dentin

A

cementum

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3
Q

______ ______ is largely composed of collagen fibers which are embedded on one end into the cementum and on the other the bony socket housing the tooth

A

periodontal ligament

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4
Q

All of the structures of the periodontium serve s an attachment apparatus for the tooth except _______ ______

A

sulcular gingiva

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5
Q

Tooth root develops _______ the crown

A

after

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6
Q

_____ ______ ____ _____ (____) guides the growth of the root

A

Hertwig’s epithelial root sheath (HERS)

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7
Q

The initiation of root dentinogenesis slightly precedes _______ development

A

periodontal

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8
Q

The inductive signal from HERS for odontoblast differentation is _________ and/or _______

A

TGF-B and/or laminin5

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9
Q

Once dentin in the root begins to be laid down, _____ separates from root dentin. Cells migrate to root dentin to become _________, to site of future tooth socket to become ______ and to the future PDL to become ________

A

HERS
cementoblasts
osteoblasts
fibroblasts

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10
Q

______ & ________ secrete their organic matrix composed primarily of type I collagen then the ______ _______ secrete their own organic collagen matrix

A

Cementoblasts & osteoblasts

PDL fibroblasts

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11
Q

The organic matrices of cementum and bone are secreted before _________ begins

A

mineralization

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12
Q

As the PDL fibers are secreted they intermingle in _________ matrices then become entrapped in those matrices during ______ in the cementum on one side and the alveolar bone on the other

A

unmineralized

mineralization

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13
Q

All of periodontal development, including PDL development, is occurring as the tooth is ______

A

erupting

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14
Q

As the tooth is erupting, _______ fibers of the PDL get added apically, the ______ of PDL fibers also change

A

collagen

orientation

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15
Q

Collagen fiber bundle starts in an ______ orientation with ends embedded in the cementum more ______ positioned. Then to a more _________ position, then _____ again with the cementum more ______

A 
oblique 
apically
horizontal
oblique
coronal
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16
Q

The periodontium growth proceeds from the _____ to the ______ ______ occurring simultaneously with eruption. 2 processes are coordinated and slow

A

CEJ

root apex

17
Q

_______ cementum is the first type of cementum formed, mainly acellular, located on coronal ____ of root

A

Primary

2/3

18
Q

________ cementum is fromed after @ least ____ of the root is formed to the time the tooth emerges in the oral cavity, mainly cellular, located on apical ____of root

A

secondary
1/2
2/3

19
Q

_________ cementum is most important in serving an attachment function

A

primary

20
Q

The 2 types of cementum overlap in the ______third of the root, with _____ cementum overlying ______ cementum

A

middle
secondary
primary

21
Q

Along the advancing root edge, there is the continuous stretch of predentin extending btw the future _____ and the _____

A

DCJ

pulp

22
Q

A little coronal to the tip of the developing root, the root dentin starts to _______ creating _____, separate ______parts of dentin: the ______ adjacent to the pulp and another region at the future _____

A 
mineralize
two
unmineralized 
predentin
DCJ
23
Q

_____ ______ a dense group of collagen fibers oriented at _______ angles to the DCJ

A

fiber fringe

right

24
Q

The fiber fringe extends into the _______ ______ ____ . Upon mineralization the fiber fringe is embedded within the mineralized dentin matrix

A

unmineralized dentin matrix

25
Q

The firm attachment between the cementum and _____ is a consequence of the ______ ______ of these 2 tissues _______ prior to mineralization

A

dentin
collagen fibers
intermingling

26
Q

As cementoblasts secrete primary cementum the cementoblasts _____ become entrpped in the ECM they are making (acellular); rather they _____toward the location of the future PDL (cellular)

A

don’t

retreat

27
Q

The adult PDL contains remnants of the Hertwig’s epithelial root sheath called _____ ______ ___ ______

A

epithelial rests of Mallasez

28
Q

What are the similarities between cementogenesis of primary and secondary cementum?

A

DCJ formed in same way- collagen fibers of cementum (fiber fringe) + dentin intermingle prior to mineralization

29
Q

What are the differences between cementogenesis of primary and secondary cementum?

A

cementoblasts become trapped in secondary cementum matrix (called cementocytes) bc deposited more rapidly
(cellular secondary cementum)

30
Q

Sulcular epithelium arises from embryonic ____ _______ and junctional epithelium arises from _______ ______ ____

A

oral epithelium

reduced enamel epithelium

31
Q

All cells of the connective tissue components of the periodontium (PDL, bony tooth socket, cementum) arise from precursor cells of ______ ______

A

dental follicle

32
Q

_________ may arise from the follice or from HERS cells that undergo epithelial-mesnchymal transformation

A

cementoblasts

33
Q

Cementoblasts may derive from both ______ AND _____ ______

A

HERS

dental follicle

34
Q

______ are secreted growth factors (signaling molecule) belonging to TGF-B superfamily

A

BMPs (bone morphogenic proteins)

35
Q

______ is transcription factor implicated in cementoblast differentiation

A

RunX

36
Q

______ _____and ____ are both secreted from cementoblasts about the same time as the initial collagen matrix: role in mineralization

A

Bone sialoprotein

osteopontin

37
Q

_______ _____ may play a role in cementoblast adhesion to the root dentin surface and in triggering the mineralization of cementum but they also bind to _______

A 
bone sialoprotein (BSP)
collagen

Oral Histology (16 decks)

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