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Oral Histology > Ex 1- Odontogenesis > Flashcards

Ex 1- Odontogenesis Flashcards

1
Q

_______ is the formation of tooth tissues from stem cells originating in the ________ primary germ layer

A

Odontogenesis

Ectoderm

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2
Q

Odontogenesis begins in the ______ embryonic week

A

6th

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3
Q

What are the two basic tissues that arise from the ectoderm primary germ layer that are involved in tooth development?

A

Epithelium

Mesenchym

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4
Q

_______ is the formation of dentin tissue

A

Dentinogenesis

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5
Q

______ is the formation of enamel tissue

A

Amelogenesis

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6
Q

_____ is the formation of cementum tissue

A

Cementogenesis

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7
Q

Formative levels of the odontogenic epithelial and mesenchymal tissues appear ______ tooth mineralized tissue

A

before

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8
Q

What is the order in which tooth tissues form?

A

dentin
enamel
cementum

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9
Q

What are the two histologic stages of odontogenesis?

A

epithelial stage

tooth germ stage

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10
Q

What are the 4 stages of the epithelial stage?

A
  1. epithelial dental lamina
  2. epithelial bud
  3. epithelial cap
  4. epithelial bell (enamel organ)
    * epithelial bell stage- epithelium is 4 distinct layers
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11
Q

The _____ ______ stage is when odontogenic epithelial and mesenchymal tissues combine inducing specificity to become formative cells of dentin, enamel, cementum, and pulp tissues

A

Tooth germ

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12
Q

What are the three parts of the tooth germ?

A

Enamel organ (bell)
Dental papilla
Dental follicle
* give rise to the specialized cells that form tooth tissues

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13
Q

What tissues make up the 3 parts of the tooth germ?

A
  • epithelium- enamel organ

- mesenchyme- dental papillla + follicle

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14
Q

During the ___ embryonic week, two epithelial invaginations appear (vestibular lamina + primary dental lamina) in the lower anterior region of the lower jaw and later in the week the upper jaw

A

6th

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15
Q

The epithelial invaginations descend into the underlying mesenchymal tissue (ectomesenchyme) and continue _______ within the mesenchyme as continuous epithelial bands

A

posteriorly

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16
Q

The ______ arch is 1/2 week behind the _____ arch in terms of development

A

maxillary

mandibular

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17
Q

The facial band is called ______ lamina

A

vestibular

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18
Q

The lingual band is called ______ ____ lamina

A

primary dental

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19
Q

In the most facial epithelial band, _______ lamina, cell death will occur in the center leaving a space known as the ______

A

vestibular

vetibule

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20
Q

In the lingual most epithelial band is the odontogenic ______ ______ lamina, cells arising from this lamina (primary and secondary) become the odontogenic ________ part of a tooth _____

A

primary dental
epithelium
germ

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21
Q

Cells at the deep end of the dental lamina, where a tooth is destined to form, will develop into epithelial knobs, each known as an _____ _____ which is surrounded by _______ tissue

A

epithelial bud

mesenchymal

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22
Q

What is the first mineralized tissue of a tooth?

A

Dentin

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23
Q

Epithelial bud cells are continuous with cells of the ____ _____ ____

A

primary dental lamina

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24
Q

Primary buds of central incisors form ___ weeks in utero

A

6

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25
Q

Primary buds of second molars form ___ weeks in utero

A

8

26
Q

How many primary buds are there per arch?

A

10

27
Q

Permanent buds of first molars form __ months in utero

A

4

28
Q

Permanent buds of central incisors form __ months in utero

A

5

29
Q

Permanent buds of second molars form __ moths postnatally

A

10

30
Q

Permanent buds of third molars form __ years postnatally

A

5

31
Q

There is __ primary dental lamina per arch and __ secondary dental lamina per arch for each succedaneous teeth

A

1

10

32
Q

A total of __ epithelial buds arise from the primary dental lamina of each arch: __ primary teeth and __ permanent molars

A

16
10
6

33
Q

Each succedanous tooth has its own _______ dental lamina that arises from the _____ side of the primary dental lamina

A

secondary

lingual

34
Q

During the cap stage epithelial cells of the cap concentrate to form an ______ _____ which acts as a _______ _____

A

enamel knot

signaling center

35
Q

The _____ _____ determines if a tooth will develop to become an anterior or posterior tooth

A

signaling center

36
Q

During the epithelial bell stage the epithelial cap undergoes growth and develops into a ___ shaped epithelial structure called an ______ ______

A

enamel organ

37
Q

At the bell stage, the epithelium is arranged into ___ distinct cell layers; given names according to position within the bell and cell morphology

A

4

38
Q

What are the 4 distinct epithelial cell layers of the enamel organ from inner to outer?

A
  1. inner epithelial layer
  2. stratum intermedium epithelial layer
  3. Stellate reticulum epithelial layer
  4. outer epithelial layer
39
Q

The ____ _____ layer becomes ameloblasts

A

inner epithelial

40
Q

Secondary dental lamina is _______ to the primary tooth germ. ___ secondary lamina arise in each arch. ___ for each secondary toth

A

lingual
10
1

41
Q

Secondary dental lamina arises from _____ _____ lamina NOT the oral epithelium

A

primary dental

42
Q

____ ____ is the epithelial enamel organ and a closely associated __________ tissue that is continuous from around the epithelium to within the epithelium

A

tooth germ

43
Q

What are the 3 distinct parts of the tooth germ?

A
  • enamel organ- epithelium
  • dental papilla- ectomesenchyme
  • dental follicle- ectomesenchyme
44
Q

The ____ ____ is avascular. Inner epithelial cells differentiate into _______ specialized epithelial cells

A

enamel organ
ameloblasts
epithelia is avascular

45
Q

After the formation of enamel is complete, the ameloblasts, along with other layers of the enamel organ come together over the surface of the enamel as a protective structure called ______ _______ ____

A

reduced enamel epithelium

46
Q

The _____ ____ is vascular. Its undifferentiated (stem) cells become ____, ____, and _____ ____

A

dental papilla
odontoblasts
fibroblasts
reserve cells

47
Q

Dental papilla ultimately becomes ____ tissue of the tooth. _____ are the most numerous cells in the ____ tissue

A

pulp
fibroblasts
pulp

48
Q

The dental follicle is avascular. Its stem cells become ______, ____, _____, and _____ ____

A

cementoblasts
fibroblasts
osteoblasts
reserve cells

49
Q

The dental follicle ultimately becomes the ______ _____ of the periodontium

A

periodontal ligament

50
Q

The enamel organ is attached to both mesenchymal parts of the tooth germ by a _____ _____

A

basal lamina

51
Q

The light, acellular layer between odontoblasts and ameloblasts is the site of the future ______ junction (___)

A

dentinoenamel junction

DEJ

52
Q

The __ cell layers of enamel organ come together to form a stratified epithelial layer over the enamel surface called ______ _______ epithelium that protects the enamel from surrounding connective tissue until the tooth enters the ______ _____

A

4
reduced enamel
oral cavity

53
Q

The ______ _____ at the rim of the epithelial bell (enamel organ) is where inner and outer cell layers merge

A

cervical loop

54
Q

Outer and inner layers come together at the cervical loop forming a double epithelial layer called ______ ______ ______ _____

A

Hertwig’s epithelial root sheath

55
Q

Hertwig’s epithelial root sheath has what 2 functions?

A
  • Determines:
  • root dentin outline
  • # root canals of toth
56
Q

What part of the germ layer and what formative (blast) cell types arose from pulp stem cells?

A

Dental papilla

  • odontoblasts
  • fibroblasts
57
Q

The periodontal ligament was from what part of the germ layer and what 3 formative (blast) cell types arose from its stem cells?

A

Dental follicle

  • fibroblasts
  • cementoblasts
  • osteoblast
58
Q

Osteoblasts come from _____ cells while osteoclasts come from _____ _____

A

stem

bone marrow

59
Q

What parts of the tooth germ are avascular and vascular?

A

Enamel organ- avascular

Dental papilla + follicle- vascular

60
Q

The dental papilla of the primary first molar forms the secondary dental papilla of the permanent first _______

A

premolar

Oral Histology (16 decks)

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