Erythrocyte Morphology/Nomenclature and Inclusion Flashcards
2-10 pointed projections of various lengths and irregular spacing; intensely stained
Acanthocyte
Spur cells
Alcohol intoxication (Zieve’s syndrome) Pyruvate kinase deficiency Abetalipoproteinemia, congenital Vitamin E deficiency Post splenectomy
Acanthocytes
Spur cells
2-10 intensely stained projections
Contains one or more vacuoles that resemble a blister on the skin
Blister Cell
10-30 pointed projected EVENLY DISTRIBUTED around the cell
Burr Cell
Echinocyte
Crenated RBC
Post splenectomy patients
with enzyme anomalies
Artificial drying
Burr cells
Echinocytes
Crenated RBC
Narrow and elongated
Resembling a rod or cigar shape
Elliptocyte
Pencil Cell
Iron Deficiency Anemia
Hereditary elliptocytosis
Idiopathic myelofibrosis
Elliptocyte
Pencil cell
Fragment in which the volume is close to normal
Keratocyte
Horned cell
Helmet cell
G6PD deficiency
Pulmonary emboli
Keratocyte
Horned cell
Helmet cell
Narrow band of hemoglobin across the center of the cell
Knizocyte
Pinch bottle cell
Oval or egg-like in appearance
Ovalocyte
Elliptocyte
Myelodysplastic syndromes
Thalassemia syndromes
Megaloblastic process
Ovalocyte
Elliptocyte
Fragment in which cellular volume is reduced
Schistocyte
Schizocyte
Prosthetic heart valves
Microangiopathic hemolytic anemia (DIC, TTP, HUS)
Clostridial infection
Schistocyte
Schizocyte
Crescent shaped with at least one end that is pointed
Sickle cell
Drepanocyte
Sickle Cell Anemia
Hemoglobin C harlem
Sickle cell
Drepanocyte
Any cell with projections
Spiculated RBCs
Myelofibrosis
Uremia
Post-splenectomy states
Spiculated RBCs
Compact and round; has lost its area of central pallor and stains intensely
Spherocyte
Immune hemolytic anemias
Hereditay spherocytosis
Post-transfusion
Possible pathology
Spherocyte
Central slit-like opening resembling a mount
Stomatocyte
Stomatocytosis
Stomatocyte
Contains central bull’s eye surrounded by a clear ring and then an outer red ring
Target cell
Codocyte
Hemoglobin C disease Hemoglobin C Trait Post-splenectomy Liver disease IDA Thalassemua Hemoglobin SC LCAT DEFICIENCY
Target cell
Codocyte
Resembles a tear
Has one elongated end
Teardrop cell
Dacrocyte
Myelofibrosis
Teardrop cell
Dacrocyte
Single, occasionally double, rarely multiple
Red purple coccoid bodies, 1-2 um in diameter
DNA: nuclear or chromosomal remnant
Seen in Megaloblastic anemia
Hyposplenism
Howell-Jolly body
Clusters of small blue coccoid bodies located at the periphery of the cell
Non-heme iron
Seen in sideroblastic anemia
Hemolytic anemia
Pappenheimer body
Multiple, uniform, dark dots
distributed evenly throughout the cell
Altered RNA
Seen in lead or heavy metal intoxication after treatment for iron deficiency or megaloblastic anemia
Basophilic stippling
Red-purple ring at the periphery of the cell
May be in the form of a figure 8
Mitotic spindle remnant
Hyposplenism anemia
Cabot ring
Invisible
Denatured, precipitated hemoglobin
G6PD Deficiency Hb which other hemolytic anemia
Heinz-Ehrlich body
