Epithelial Tissues Flashcards
Prelims
It has several long secretory portions that join together to drain in 1 duct.
Simple Branched Tubular
They have epithelial ducts carrying their secretions to specific sites.
Exocrine Glands
It involves the release of products by means of exocytosis at the apical end of the secretory cells.
Merocrine Secretion
What are the 4 Basic Tissue Types?
- Epithelial
- Connective
- Muscle
- Nervous
Elaborate the characteristics of Epithelial Tissue
- Variable in shape and dimensions
- The cells’ size and morphology is dictated by their function.
- Nuclei vary in shape, and corresponds to the cell shape.
- The number and shape of stained nuclei is an indicator of the cells’ shape and density which is an important criterion for classifying epithelia.
- Polarity
- Lie at the basement membrane
- Avascular
Which Type of Epithelium?
- Conjunctiva
Stratified Columnar
What are the 2 main functions of an epithelial tissue?
- Lining of surface or body cavities
- Glandular secretion
What are the transmembrane link proteins found in gap junctions?
Connexins
These are larger projecting structures with a well-organized core of microtubules that propel material along a surface.
Cilia
Which Type of Epithelium?
- Urinary Tract
Transitional
Which Type of Epithelium?
- Trachea
Ciliated Pseudostratified Columnar
Oligosaccharide components of mucus stain well with _________.
PAS stain
Which Type of Epithelium?
- Skin
Stratified Squamous Keratinized
A square/cuboid shape of of the cell
Cuboidal
It faces the lumen (space).
Apical Pole
How can we describe the amount of extracellular matrix in epithelial tissue?
Small
How can we describe the amount of extracellular matrix in muscle tissue?
Moderate
Which Type of Epithelium?
- Uterine Tube
Simple Columnar
A layer of the ovaries and seminiferous tubules.
Germinal Epithelium
Give an example of Merocrine secretion
Most exocrine glands
It is made up of flat cells that lines the blood vessels.
Endothelium
These are exocrine glands producing mucus.
Mucous Glands
These are glands that do not have their ducts branch.
Simple Glands
What are examples of simple coiled tubular glands?
Sweat glands
Elaborate the functions of Epithelial Tissue
- Lining and covering of internal and external surfaces
- Protection against abrasion and injury
- Absorption of materials
- Transportation of materials
- Gas exchange
- Secretion
- Lubrication
Which Type of Epithelium?
- Lining of Loop of Henle
Simple Squamous
What are the main functions of a connective tissue?
Support and protection of tissues/organs
It functions in the synthesis and secretion of specialized products.
Secretory Epithelia and Glands
A thin meshwork of type IV collagen and laminin produced by the epithelial cells.
Basal Lamina
Which Type of Epithelium?
- Urinary Bladder
Transitional
How can we describe the cells of nervous tissue?
Elongated with extremely fine processes
How can we describe epithelial cells?
Aggregated, polyhedral cells
What are examples of simple branched tubular glands?
Glands in the uterus and stomach
These are glands that have their ducts branch.
Compound Glands
It is a tissue in which cells are bound tightly together to form a sheet-like or tubular structure.
Epithelial Tissue
What are the main functions of muscle tissue?
Strong contraction and body movements
Why do serous glands stain darkly with H&E?
Because of its RER and secretory granules.
These are small membrane proteins that increases epithelial cell’s apical surface area for absorption.
Microvilli
Which Type of Epithelium?
- Lining of Kidney Tubules
Simple Cuboidal
What are the apical structures found on epithelial cells?
Microvilli, Stereocillia, and Cilia
Which Type of Epithelium?
- Glomerular Capsule
Simple Squamous
Elaborate the different classes of Simple Glands
- Simple Tubular
- Simple Branched Tubular
- Simple Coiled Tubular
- Simple Acinar
- Simple Branched Acinar
It secretes mucus and creates a layer of protection.
Goblet Cells
It seals adjacent cells to one another, controlling the passage of molecules between them, and separates the apical and basolateral membrane domains.
Occluding or Tight Junctions
Which Type of Epithelium?
- Ducts of Sweat Glands
Stratified Cuboidal
Which Type of Epithelium?
- Vagina
Stratified Squamous Non-Keratinized
Which Type of Epithelium?
- Anal Canal
Stratified Squamous Non-Keratinized
What are the functions of the basement membrane?
- Attach the epithelia to the connective tissue
- Regulate (filter) substances
- Provides a guide or scaffold during tissue generation
- Compartmentalize epithelial cells
Which Type of Epithelium?
- Fallopian Tube
Ciliated Simple Columnar
Which Type of Epithelium?
- Small Intestine
Simple Columnar
How can we describe the amount of extracellular matrix in nervous tissue?
Very small
It has an elongated secretory portion, and its duct is usually short or absent.
Simple Tubular
Which Type of Epithelium?
- Bowman’s Capsule
Simple Squamous
Which Type of Epithelium?
- Bronchi
Pseudostratified Columnar
It involves the loss of membrane-enclosed apical cytoplasm.
Apocrine Secretion
Which Type of Epithelium?
- Endothelium
Simple Squamous
It has ducts of both tubular and acinar secretory units converge at larger ducts.
Compound Tubuloacinar
Give an example of Holocrine secretion
Sebaceous glands
Basket cells, to remodel scars in the skin.
Myoepithelium
What are the two parts of the basement membrane?
Basal Lamina and Reticular Lamina
What is the main function of the nervous tissue?
Transmission of nerve impulses
It is a 6 protein-subunit that makes up the connexons.
Connexins
These are glands that lack ducts.
Endocrine Glands
Which Type of Epithelium?
- Esophagus
Stratified Squamous Non-Keratinized
How are the secretions of endocrine glands carried and transported?
Via the interstitial fluid and blood
How many microtubules does an axoneme have?
11
What are the transmembrane link proteins found in adherent junctions?
E-cadherin and catenin complex
What are the 5 types of Junctional Complexes?
- Occluding or Tight Junctions
- Adherent Junctions
- Desmosomes or Macula Adherens
- Hemidesmosomes
- Gap or Communicating Junctions
What are examples of simple tubular glands?
- Mucous glands of the colon
- Intestinal glands or crypts
What are the 3 Modes of Secretion by glands?
- Merocrine
- Holocrine
- Apocrine
It anchors the cytoskeleton to the basal lamina.
Hemidesmosomes
What are examples of compound acinar glands?
Exocrine Pancreas
It has a rounded, saclike secretory portion.
Simple Acinar
What are examples of compound tubuloacinar glands?
Salivary glands
What are the transmembrane link proteins found in desmosomes?
Cadherin Family (desmogleins, and desmocollin)
Transitional Epithelium or Urothelium is under _________.
Stratified Epithelium
Classification of Epithelia Based on Cell Shape
- Squamous
- Cuboidal
- Columnar
A serous lining of cavities such as pericardium, pleura, and peritoneum.
Mesothelium
How can we describe the cells of muscle tissue?
Elongated contractile
Which Type of Epithelium?
- Cervix
Stratified Squamous Non-Keratinized
It faces the connective tissue and basement membrane.
Basal Pole
It allows direct transfer of small molecules and ions from one cell to another.
Gap or Communicating Junctions
Which Type of Epithelium?
- Mouth
Stratified Squamous Non-Keratinized
It is the lining of the uterus.
Endometrium
Which Type of Epithelium?
- Mesothelium
Simple Squamous
What are the transmembrane link proteins found in hemidesmosomes?
Integrins
Classification of Epithelia Based on Function (functional epithelium)
- Mesothelium
- Endothelium
- Myoepithelium
- Endometrium
- Germinal Epithelium
- Glandular Epithelium
Together, the _______ and ________ attach the epithelia to the connective tissue.
Basal and Reticular Lamina
It is responsible for the movement of cilia.
Axoneme
What are examples of simple acinar glands?
Small mucous glands along the urethra
It functions in secretions.
Glandular Epithelium
Which Type of Epithelium?
- Thyroid
Simple Cuboidal
How can we describe the amount of extracellular matrix in connective tissue?
Abundant
Which Type of Epithelium?
- Lining of the Stomach
Simple Columnar
All the substances that enter or leave an organ must cross this type of tissue.
Epithelial Tissue
What are the transmembrane link proteins found in tight junctions?
Occludins, claudins, and ZO proteins
Classification of Epithelia Based on the Number of Cell Layers
- Simple Epithelium
- Stratified Epithelium
Give an example of Apocrine secretion
Mammary glands
Pseudostratified Epithelium is under _________.
Simple Epithelium
Classification of Epithelia Based on the Surface Modification of the Cell
- Ciliated
- Keratinized/Non-Keratinized
It has several elongated coiled secretory units and their ducts converge to form larger ducts.
Compound Tubular
A tall and rectangular shape of the cell
Columnar
It contains type III collagen and anchoring fibers of type VII collagen.
Reticular Lamina
Oligosaccharide components of mucus stain poorly with _________.
routine dyes
Which Type of Epithelium?
- Male Urethra
Stratified Columnar
A flat-shaped cell
Squamous
Which Type of Epithelium?
- Gallbladder
Non-ciliated Simple Columnar
It has multiple saclike secretory portions entering the same duct.
Simple Branched Acinar
It provides points linking the cytoskeleton of adjacent cells, and strengthens and stabilizes nearby tight junction.
Adherent Junction
What are examples of compound tubular glands?
Submucosal mucous glands in the duodenum
Which Type of Epithelium?
- Alveoli
Simple Squamous
Which Type of Epithelium?
- Ducts of Glands
Simple Cuboidal
How can we describe the cells of connective tissue?
Fixed and wandering
These are exocrine glands producing largely enzymes (proteins).
Serous Glands
It has several saclike secretory units with small ducts converge at a larger duct.
Compound Acinar
It is a thin extracellular layer of specialized proteins, which also acts as a semipermeable filter for substances reaching epithelial cells from below.
Basement Membrane
What are examples of simple branched acinar glands?
Sebaceous glands
It is produced by the disintegration of the secretory cells themselves as they complete their terminal differentiation, which involves becoming filled with the product.
Holocrine Secretion
Its secretory portion is very long and coiled.
Simple Coiled Tubular
These are long microvilli with specialized mechanosensory function, which also increases surface area for absorption; longer and less motile with distal branches.
Stereocillia
It provides points of strong intermediate filaments coupling between adjacent cells, which strengthens the tissue.
Desmosomes