Connective Tissue Flashcards
Why are reticular fibers PAS +?
Due to their high sugar content
It provides a framework for cells in the hematopoietic tissue and lymphoid organs.
Reticular Connective Tissue
A substance released by mast cells that acts as an anti-coagulant.
Heparin
Dendritic cells are typically found in the _________.
Lymph nodes, spleen
It features bundles of essentially parallel type I collagen, providing great strength (but little stretch) in binding together components of the muscoskeletal system.
Dense Regular Connective Tissue
Reticular fibers stain poorly with _________.
H&E
Where is type 3 collagen prominent?
Cellular tissues such as lymphoid organs, liver, and bone marrow
It is an amorphous, semi-solid gel, transparent material that fills the space between cells and fibers in the connective tissue.
Ground Substance
Reticular Connective Tissue is produced by ___________.
Modified fibroblasts called “reticular cells”
The main structural collagen of hyaline cartilage and consists of fibrils in the cartilage ground substance.
Type 2
Where are Loose Connective Tissue usually found?
Surrounds small blood vessels, and adjacent to other types of epithelia
They originate from blood cell precursors and are filled with granules for the release of various vasoactive agents and other substances during inflammatory and allergic reactions.
Mast Cells
Connective tissue is the _______ tissue in the body.
most abundant
Microglial cells are typically found in the _________.
Central Nervous System (CNS)
Reticular Fibers originated from _________.
Type 3 Collagen
It has binding sites for integrins, type IV collagen, and specific proteoglycans, providing adhesion for epithelial and other cells.
Laminin
A key proteoglycan in all basal laminae.
Perlecan
It synthesizes and secretes the components of ECM.
Fibroblasts
The _________ is the major constituent of connective tissue.
Extracellular Matrix
They provide surveillance against bacterial invaders and stimulating tissue repair.
Leukocytes
It is the main fiber type found in most supporting tissue.
Collagen
It is the inactive form of fibroblasts.
Fibrocytes
How would you describe the appearance of Mucoid Tissue?
- Abundant ground substance
- Sparse Collagen Fibers
- Scattered Fibroblasts
The binding sites for collagens and certain GAGs, and forms insoluble fibrillary networks throughout connective tissue.
Fibronectin