Epithelial Flashcards

1
Q

What are the four types of tissues?

A

Epithelia
Connective
Muscle
Nervous

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2
Q

Three primary germ layers:

A

ectoderm
mesoderm
endoderm

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3
Q

General features of epithelia

A

-little extracellular material
-closely packed cells with specialized junctions
-avascular
-innervated
-apical surface exposed to body or organ cavity
-basal surface attached to basement membrane

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4
Q

The process where one cell type changes into a different one:

A

Metaplasia

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5
Q

What are carcinomas?

A

Tumors that arise from surface epithelia

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6
Q

What are adenocarcinomas?

A

Tumors that arise from glands

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7
Q

Functions of epithelia

A

-prevention of desiccation
-protection
-filtration
-secretion
-absorption
-sensory reception

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8
Q

Epithelium that lines cavities that connect to the outer world

A

muscous membrane

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9
Q

Layers of muscous membrane

A

-ectoderm (endoderm)
-basement membrane
-connective tissue (lamina propria)
-smooth muscle (muscularis mucosae)

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10
Q

epithelium that lines closed body cavities

A

serous membrane

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11
Q

Layers of serous membrane

A

-epithelial lining
-mesothelium
-basement membrane
-connective tissue

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12
Q

Four types of apical specialization

A

-microvilli
-sterocilia
-cilia
-flagella

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13
Q

Microvilli

A

surface specialization to increase cell surface area for absorption or secretion

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14
Q

What is the terminal web?

A

In the basement membrane that anchor the microvilli onto the cell
-made of cytokeratin filaments

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15
Q

Stereocilia

A

very long, non-motile microvilli
-rigid due to core of actin filament
-absorption and secretion

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16
Q

Cilia

A

-mobile, hair-like projections specialized for coordinated movement
-extension of cytoskeleton
-movement of fluids and particulate matter

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17
Q

axoneme

A

core of microtubules
(9+2 doublets)
anchored by basal body

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18
Q

Immotile ciliary syndrome

A

-genetic defect that causes uncoordinated or absent cilia
-recurrent/severe chest infection
-infertility
-hydrocephalus

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19
Q

Flagella

A

spermy

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20
Q

lateral surface specializations

A

-tight junctions
-adhering junctions
-desmosomes
-gap junctions (connexons)

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21
Q

Tight junction

A

fluid tight seals that do not allow anything in the cell or around that part of lateral portion
-present

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22
Q

Adherens junctions

A

fastens cell to one another
-beneath tight junctions
- dense plagues of myosin, tropomyosin, and vinculin
-integrins are also involved

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23
Q

Desmosomes

A

-cytokeratin filaments for shearing forces
-plaques that attach surfaces on opposing membrane
-mediated by transmembrane proteins- desmogleins

24
Q

Hemidesmosome

A

-basal surface of cell
-anchor to basement membrane of integrins
-plaque and keratin tonofilaments

25
Q

Communicating/gap junctions

A

allow rapid spread of information
-circular connexons in membrane
-permit passage of small molecules between adjacent cells

26
Q

Basement membrane

A

narrow, acellular interface between epithelium and connective tissue

27
Q

Major components of basement membrane

A

-GAGs (heparan sulfate)
-Type IV collagen
-structural glycoproteins (laminin, fibronectin, and entactin)

28
Q

Three layers of basement membrane

A

-lamina lucida
-lamina densa
-lamina reticulus

29
Q

Simple squamous epithelium

A

flat cells and flat nuclei

30
Q

simple cuboidal epithelium

A

one layer of square cells with round nuclei

31
Q

simple columnar epithelium

A

one layer of rectangle cells with oval nuclei
-can have cilia

32
Q

pseudostratified columnar

A

there is some random cells in random places

33
Q

statified squamous nonkeratinized

A

multiple layers of flat cells that still have nuclei on the outer most cell

34
Q

stratified squamous keratinized

A

multiple layers of flat cells that do not have visible nuclei in the top layer of cells

35
Q

stratified cuboidal epilthelium

A

multiple layers of square looking cells

36
Q

stratified columnar epithelium

A

multiple layers of rectangle cells

37
Q

Transitional epithelium

A

allow for stretching of the epithelium
-have a cap, dome, or umbrella cells
-lots of desmosomes

38
Q

Simple glands

A

unbranched ducts

39
Q

compound glands

A

branched ducts

40
Q

Tubular glands

A

tube like (straight or coiled)

41
Q

Acinar glands

A

sac-like or flask-shaped

42
Q

Tubuloacinar

A

intermediate- tube with dilated end

43
Q

Endocrine glands

A

release straight into the blood stream

44
Q

exocrine glands

A

release product into ducts

45
Q

goblet cells

A

specialized, unicellular exocrine glands
secrete mucus

46
Q

merocrine

A

only secretory product released

47
Q

apocrine

A

secrete membrane bound vesicles; accompanied by some cytoplasm

48
Q

What is the most common type of gland?

A

Merocrine

49
Q

What type of glands are sweat and mammary glands?

A

apocrine

50
Q

holocrine

A

entire cell secreted (ruptures, releases content)

51
Q

What type of glands are sebaceous glands?

A

holocrine

52
Q

what type of gland is this?

A

endocrine

53
Q

what types of glands are these?

A

exocrine

54
Q

what type of gland is this?

A

merocrine

55
Q

what type of gland is this?

A

apocrine

56
Q

what type of gland is this?

A

holocrine