Epi Cell Bio and the Cell Cycle Flashcards

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1
Q

what si epi

A

tissue of closely packed cells that forms a surface or lines of cavity or tube
line surfaces
protective
secretary

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2
Q

how ar epi cells classed num layers

A

num layers
- one - simple or multi (pseudostratfeid)
2/more - stratified

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3
Q

how are epi cells classed by shape

A

flattened - squamous
cubes - cuboidal
columns - columnar

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4
Q

what si the function of oral mucous epi

A

protect
perm barrier
protect fluid loss

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5
Q

what si a standard strutter of epi cell

A
basla lamina 
hemidesmosome 
desmosome 
keratin filaments
nu c
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6
Q

what binds two epi cells together

A

desmosomes - communications done though this also

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7
Q

where is basal lamina

A

between mesenchyme
and epi
allowing interaction with underlying storm

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8
Q

what is cell rpoliferation

A

an increase in the number of cells asa result of cell growth and cell divison

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9
Q

wha kind of epi is oral mucosa

A

stratified squamous epi

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10
Q

wehre is masticatory oral mucosa

A

gingival and hard palate

keranised

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11
Q

whereis lining oral mucosa

A

floor mouth
buccal regions
oes non keratinised

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12
Q

where is some specialised oral muscos

A

dorsum of tongue

both keratinise and non

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13
Q

how does a cell reproduce

A

by eprfomrig orderly sequence of events which duplicates content then divides into two

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14
Q

what is a simple cell cycle

A

chromosome replication and cell growth

chromo segregation

cell division

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15
Q

how si the cells cel ontorlled

A
timer
order
on off switch 
robustness 
adaptability
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16
Q

what re the phases

A

G1
S
G2
M

17
Q

what are the cell cycle checkpoints

A

G1 - enviro fave?
G2 - dna rep
M - chromos on spindle

18
Q

what are the phases of interphase onwards

A
prophase 
metaphase
anaphase 
telophase
cytokinesis
19
Q

what are some cell cycle ‘controllers’

A

protein kinases
cyclin dept kinases
phosphorylation proteins

20
Q

what are cyclin dept kinases controlled by

A

CYCLIN

21
Q

what happens to cyclins during cell cycle

A

circle of synthesis

22
Q

what are cyclin classes

A

4 classes

  • G1/s at end G1 - dna replication
  • S bind Cdk’s during s = imitate dna rep
  • M - mitosis
23
Q

what si he cyclin complex for cyclin D

A

G1/Cdk

24
Q

what si he cyclin complex for cyclin E

A

G1-S CdK

25
Q

cyclins dont only activate cdk but

A

directs it

26
Q

what si a growth factor

A

polypeptides that control animal cel grown and diff

store and rel into ECM

27
Q

wat is a transcription factor

A

protein tha regulates the activity of RNA polymerase

28
Q

what is the proliferation control

A

receptors
signalling
ECM
phosphorylation

29
Q

what does a cell proliferation unit have

A

progenitor cells basal cell layer

divide to clusters

30
Q

what is cell cycle cyclin over expression always

A

phsophsyrlaed

31
Q

what is the guardian of genome

A

P53

32
Q

what are stem cels

A

not terminally diff
divide withoutlimt
each daughter cell has a choice