CellStructure and Acinar Mechanisms Flashcards
constituents of saliva
water
inorganic
organic
what are the series of ducts
secretary
striated
intercalated
acinus
what are the secretary end pieces
pyramidal shaped cells which are polarised for function
what are the types of acing cells
serous
mucous
mixed
what is the structure of serous acini
pyrMID
MANY CELLULAR COMPS INSIDE
what is the structure of mucous acinus
columnar
nuc squeezed at basal lamina
filled with mucous granules
what is an sp strutter of mixed acinus
serous demilune and mucous cell
describe serous acing cells
nuc at basal part
basophilic RER
granular
where do serous discharge sec
into tubular lumen via intercellular cannaliculi running between cells
what is the cyto like in mucous acing cells
mucin in there
granules dehydrated so expand the released in saliva
what is the nucleus like in mucous acinar cells
flattened basal nucleus
a serous demilune in a mixed acinus discharges via
intercellular cannaliculi between mucous cells
where are myoepithelial cells
on acini and intercalated ducts
what are the functions of myoepithelial cells
contractile squeeze secretion
regulate duct lumen diameter
protection of acinus/nitercalated from pressure related damage
what are the intercalated ducts structure
low cuboidal cells
large central nucleus
difficult to see
connection only
why is the truture of the striated duct about
not present in sublingual glands
columnar
active mod saliva
massive basal imm folds
what are the secretary ducts like
collect
large lumen
pseudo stratified
when does the secretory ducts become stratified
nar termination
merges with squamous ratified oral mucosa
what si the formation of hypotonic saliva
2 phase process
what is primary saliva
formation of an isotonic solution in the acinus
what si the initial step of saliva form
move sodium and chlorine into lumen of acinus
activation of acinar cell
increase perm of potassium
what is stage 2 of saliva form
potassium in ECF activates a sodium potassium chlorine co transporter
what is stage three of saliva form
chlorine moves through the apical mem into the lumen
what is stage 4 of saliva form
th increased conc of chlorine in the acinar fluid drags sodium to balance the charge
what are the conc of sodium chlorine and carbonate in saliva similar to
plasma
when is saliva mod
who travelling through the ducts
what is stage 2
conversion isotonic to hypotonic solution
what does stage 2 entail
active reabs of sodium nd chlorine rom lumen
active sec potassium and carbonate into the lumen
where does water stay
in the lumen as duct is impermeable t water
what is the sec of sodium into saliva like
at low flow rate = low
high flow rate = high
sec at constant rate but when goes too fast saliva sec, the sodium is sec trying to keep up… at excess
what secrets the organic components of the saliva
acini cells
explain he synthesis of the organic components of saliva
formation peptides
post translational glycosylation of peptides
process and pack
form condensed vacuoles
what is the means of saliva sec
merocrine
exocytosis
what are another 2 main secretary mechanism
apocrine - loss part cell
holocrine - loss of whole cell (sebaceous glands)
