CellStructure and Acinar Mechanisms Flashcards

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1
Q

constituents of saliva

A

water
inorganic
organic

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2
Q

what are the series of ducts

A

secretary
striated
intercalated
acinus

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3
Q

what are the secretary end pieces

A

pyramidal shaped cells which are polarised for function

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4
Q

what are the types of acing cells

A

serous
mucous
mixed

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5
Q

what is the structure of serous acini

A

pyrMID

MANY CELLULAR COMPS INSIDE

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6
Q

what is the structure of mucous acinus

A

columnar
nuc squeezed at basal lamina
filled with mucous granules

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7
Q

what is an sp strutter of mixed acinus

A

serous demilune and mucous cell

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8
Q

describe serous acing cells

A

nuc at basal part
basophilic RER
granular

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9
Q

where do serous discharge sec

A

into tubular lumen via intercellular cannaliculi running between cells

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10
Q

what is the cyto like in mucous acing cells

A

mucin in there

granules dehydrated so expand the released in saliva

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11
Q

what is the nucleus like in mucous acinar cells

A

flattened basal nucleus

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12
Q

a serous demilune in a mixed acinus discharges via

A

intercellular cannaliculi between mucous cells

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13
Q

where are myoepithelial cells

A

on acini and intercalated ducts

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14
Q

what are the functions of myoepithelial cells

A

contractile squeeze secretion
regulate duct lumen diameter
protection of acinus/nitercalated from pressure related damage

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15
Q

what are the intercalated ducts structure

A

low cuboidal cells
large central nucleus
difficult to see
connection only

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16
Q

why is the truture of the striated duct about

A

not present in sublingual glands
columnar
active mod saliva
massive basal imm folds

17
Q

what are the secretary ducts like

A

collect
large lumen
pseudo stratified

18
Q

when does the secretory ducts become stratified

A

nar termination

merges with squamous ratified oral mucosa

19
Q

what si the formation of hypotonic saliva

A

2 phase process

20
Q

what is primary saliva

A

formation of an isotonic solution in the acinus

21
Q

what si the initial step of saliva form

A

move sodium and chlorine into lumen of acinus
activation of acinar cell
increase perm of potassium

22
Q

what is stage 2 of saliva form

A

potassium in ECF activates a sodium potassium chlorine co transporter

23
Q

what is stage three of saliva form

A

chlorine moves through the apical mem into the lumen

24
Q

what is stage 4 of saliva form

A

th increased conc of chlorine in the acinar fluid drags sodium to balance the charge

25
Q

what are the conc of sodium chlorine and carbonate in saliva similar to

A

plasma

26
Q

when is saliva mod

A

who travelling through the ducts

27
Q

what is stage 2

A

conversion isotonic to hypotonic solution

28
Q

what does stage 2 entail

A

active reabs of sodium nd chlorine rom lumen

active sec potassium and carbonate into the lumen

29
Q

where does water stay

A

in the lumen as duct is impermeable t water

30
Q

what is the sec of sodium into saliva like

A

at low flow rate = low
high flow rate = high
sec at constant rate but when goes too fast saliva sec, the sodium is sec trying to keep up… at excess

31
Q

what secrets the organic components of the saliva

A

acini cells

32
Q

explain he synthesis of the organic components of saliva

A

formation peptides
post translational glycosylation of peptides
process and pack
form condensed vacuoles

33
Q

what is the means of saliva sec

A

merocrine

exocytosis

34
Q

what are another 2 main secretary mechanism

A

apocrine - loss part cell

holocrine - loss of whole cell (sebaceous glands)