CellStructure and Acinar Mechanisms Flashcards

1
Q

constituents of saliva

A

water
inorganic
organic

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2
Q

what are the series of ducts

A

secretary
striated
intercalated
acinus

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3
Q

what are the secretary end pieces

A

pyramidal shaped cells which are polarised for function

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4
Q

what are the types of acing cells

A

serous
mucous
mixed

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5
Q

what is the structure of serous acini

A

pyrMID

MANY CELLULAR COMPS INSIDE

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6
Q

what is the structure of mucous acinus

A

columnar
nuc squeezed at basal lamina
filled with mucous granules

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7
Q

what is an sp strutter of mixed acinus

A

serous demilune and mucous cell

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8
Q

describe serous acing cells

A

nuc at basal part
basophilic RER
granular

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9
Q

where do serous discharge sec

A

into tubular lumen via intercellular cannaliculi running between cells

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10
Q

what is the cyto like in mucous acing cells

A

mucin in there

granules dehydrated so expand the released in saliva

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11
Q

what is the nucleus like in mucous acinar cells

A

flattened basal nucleus

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12
Q

a serous demilune in a mixed acinus discharges via

A

intercellular cannaliculi between mucous cells

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13
Q

where are myoepithelial cells

A

on acini and intercalated ducts

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14
Q

what are the functions of myoepithelial cells

A

contractile squeeze secretion
regulate duct lumen diameter
protection of acinus/nitercalated from pressure related damage

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15
Q

what are the intercalated ducts structure

A

low cuboidal cells
large central nucleus
difficult to see
connection only

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16
Q

why is the truture of the striated duct about

A

not present in sublingual glands
columnar
active mod saliva
massive basal imm folds

17
Q

what are the secretary ducts like

A

collect
large lumen
pseudo stratified

18
Q

when does the secretory ducts become stratified

A

nar termination

merges with squamous ratified oral mucosa

19
Q

what si the formation of hypotonic saliva

A

2 phase process

20
Q

what is primary saliva

A

formation of an isotonic solution in the acinus

21
Q

what si the initial step of saliva form

A

move sodium and chlorine into lumen of acinus
activation of acinar cell
increase perm of potassium

22
Q

what is stage 2 of saliva form

A

potassium in ECF activates a sodium potassium chlorine co transporter

23
Q

what is stage three of saliva form

A

chlorine moves through the apical mem into the lumen

24
Q

what is stage 4 of saliva form

A

th increased conc of chlorine in the acinar fluid drags sodium to balance the charge

25
what are the conc of sodium chlorine and carbonate in saliva similar to
plasma
26
when is saliva mod
who travelling through the ducts
27
what is stage 2
conversion isotonic to hypotonic solution
28
what does stage 2 entail
active reabs of sodium nd chlorine rom lumen | active sec potassium and carbonate into the lumen
29
where does water stay
in the lumen as duct is impermeable t water
30
what is the sec of sodium into saliva like
at low flow rate = low high flow rate = high sec at constant rate but when goes too fast saliva sec, the sodium is sec trying to keep up... at excess
31
what secrets the organic components of the saliva
acini cells
32
explain he synthesis of the organic components of saliva
formation peptides post translational glycosylation of peptides process and pack form condensed vacuoles
33
what is the means of saliva sec
merocrine | exocytosis
34
what are another 2 main secretary mechanism
apocrine - loss part cell | holocrine - loss of whole cell (sebaceous glands)