Ephedrine

Question 1

Indications - ephedrine

Answer 1

• Used as a temporizing measure during volume resuscitation or until a vasoactive agent can be initiated
• Persistent post-intubation hypotension

Question 2

Dosage - ephedrine

Answer 2

0.2 mg/kg IV/IO to a single max dose of 10 mg q 5 min prn

Question 3

Contraindications - ephedrine

Answer 3

Hypersensitivity to ephedrine or other sympathomimetics

Note MAOIs may increase pressor response. Tricyclic antidepressants may decrease pressor response. Effects are diminished in patients with prolonged hyperadrenergic state (e.g., sepsis, prolonged distress, trauma).