Enzymes Flashcards
catalysts
-in the absence of a catalysit, breaking breaking bonds to get reaction started takes significant energy and wont happen on its own
-raction of water wont happen at any appreicable rate without a ctalysi
enzymes
-catalysts that lower the activation energy
-do not change tge energetics or equilibrium
-by lowering activation energy, enzymes increase the rate of reacrtion
how do enzymes increase reaction rates and lower activation energy
-local concenrations of substrates are increased at the active site of the enzyme and are orientated properly for the reaction to take place
-many enzymes alter the electronic distribution of substrates
-stabalization of transition states of reaction
-some enzymes use of coenzymes or prosthetic groups
enzyme catalyzed reaction photo
feedback inhibition
-strategy to prevent too much of product being made
-end product acts as inhibitor of an early step in pathway
-will evolve binding affinity for enzyme such that it onnly binds/inhibits when levels are too high
-once end product used up, levels drop, no longer inhbits, pathway resumes