endocrine systemb Flashcards
endocrine the master gland
syn situation shape size weight
syn -hypophysis cerebrum
size -8mm ant post 12mm transverse
shape - oval
weight 500 g
situation - roof by hypiphyseal fossa /Sella tursica
floor- by 4th ventricle
relations of pitutary
superiority- 1 diaphragm of Sella 2 tuber centrum
3-optic chiasma
inferiorly-1- hypophyseal fossa
2- sphenoid air sinuses
pitutary gland divided
1 adenohypophysis
2neurohypophysis
adenohypophysis
develop from rathkes pouch
1-anterior lobe /pars anterior /pars distalis /pars glandularis
[largest part]
2– intermediate lobe /pars intermedia [smaller] avascular
3– tuberlobe /pars tuberalis
neurohypophysis
develops from floor of deincephalon
1– posterior lobe / neural lobe
2— infundibular stem
3— median eminence of tubercinarium
arterial supply for pitutary
internal carotid artery supply blood to hypophysis cerebri
superior hypophysis artery supplies ventral part of hypothalamus
and upper lower part of infundibulhm
portal vessels of pitutary
long pv drain in upper infundibulum
short pv drain in lower infundibulum
2 they carry releasing hormone
histology of pitutary
anterior lobe
1]]]]]chromophillic 50%
acidophyl 43% basophil 7%
2]]] chromophobic 50% –msh
posterior lobe a) vasopressin b) oxytocin through hypothalamohypophyseal tract
clinical pitutary
1 pitutary tumour – pressure on Sella tursica and optic chiasma
2 frolich syndrome– pressure on hypophthalamus
3 pressure on pars posterior - diabetics insipidus
4 giagantism -acidophil adenoma
5 Cushing syn - basophil
thyroid gland [sheild like ] , situation, dimensions
situated in lower part of front and side of neck
connected by isthmus
situation extent — c5 to t1
isthmus 2nd to 4th tracheal ring
lobe 4th and 5th tracheal ring
dimensions
weight 25g
lobe –5×2.5×2.5 isthmus 1.2×1.2
larger in female than male
featured of thyroid gland
apex base 2 border 3 surfaces
medial s == 2 tubes trachea oesophagus 2 muscles inferior constrictor and cricothyroud
2 never recurrent laryngeal nerve
external laryngeal nerve
lateral s== sternothyroid omohyoid sternocelomastoid sterohyoid
post s=== carotid sheath
ANT b== superior thyroid a
postbo == inferior thyroid a
arterial supply of thyroid
supplied by superior and inferior thyroid artery
venous=== superior middle and inferior thyroid vein
lymphatic == upper cervical lymphatic nodes and lower deep cervical lymphatic nodes
nerve == middle cervical ganglion
histology of thyroid
follicular cells t3 t4 — columnar active resting cuboidal
parafollicular cells – thyrocalcitonin - hyperglycemia opp to parathormone
clinal of thyroid
1 goiter 2 thyroidectomy 3 hypothyroidism– criticism and myxodems
carcinoma
suprarenal gland syn loc parts
syn — adrenal , epinephros
loc – posterior abd 🧱 wall above kidney
in epigastrium in front crus of diaphragmatic