Endocrine System Flashcards
How many cells does the human body contain?
50-100 Trillion cells
This SYSTEM can REGULATE the ENDOCRINE SYSTEM.
Nervous System
What is the endocrine system composed of?
Endocrine Glands
Hormones
These are COMMUNICATION and REGULATORY MOLECULES secreted by endocrine glands.
Hormones
How are hormones transported throughout the body?
Blood Stream
OR
Hemolymph
What are the FIVE (5) major PROCESSES controlled by hormones?
- ) Reproduction
- ) Development
- ) Energy Metabolism
- ) Growth
- ) Behavior
What is the FUNCTION OF HORMONES?
To SIGNAL TRANSDUCTION PATHWAYS
Why don’t hormones effect all cells of the body?
Because HORMONES BIND to SPECIFIC RECEPTOR proteins on TARGET CELLS.
What are the THREE (3) TYPES of HORMONES.
- ) Polypeptides
- ) Amines
- ) Steroids
The ENDOCRINE SYSTEM is responsible for ____________ and ____________.
Communication
Regulation
What are NON-STEROID HORMONES derived from?
Amino Acids
Give FOUR (4) examples of NON-STEROID HORMONES.
Epinephrine
Insulin
Erythropoietin
ADH
What are STEROID HORMONES derived from?
Cholesterol
Give TWO (2) examples of STEROID HORMONES.
Testosterone
Estrogen
Are NON-STEROID hormones HYDROPHILIC OR HYDROPHOBIC?
Hydrophilic
These are HORMONES derived from AMINO ACIDS.
Non-steroid
These are HORMONES derived from CHOLESTEROL.
Steroid
Are STEROID hormones HYDROPHILIC OR HYDROPHOBIC?
Hydrophobic
What are the TWO (2) MAIN LOCATIONS a for HORMONE RECEPTORS?
Plasma Membrane
Intracellular
NON-STEROID hormones ________(can OR cannot) enter target cells, while STEROID hormones ________ (can OR cannot).
Non-steroids CANNOT
Steroids CAN
How do NON-STEROID hormones TRIGGER RESPONSES in SECONDARY MESSENGER SYSTEMS? Directly OR indirectly?
INDIRECTLY, bc they cannot enter target cells.
How do STEROID hormones TRIGGER RESPONSES in SECONDARY MESSENGER SYSTEMS? Directly OR indirectly?
DIRECTLY, bc they can enter target cells.
This process is characterized by one hormone TRIGGERING the synthesis of LARGE NUMBER of ENZYMES.
Enzyme Amplification
How many MOLECULES does ONE (1) EPINEPHRINE molecule essentially activate according to ENZYME AMPLIFICATION?
1 epinephrine molecule activates 1BILLION MOLECULES
Why is it possible for the SAME HORMONE to cause DIFFERENT EFFECTS if they bind to SPECIFIC RECEPTORS?
- ) Same receptor but different intracellular proteins
- ) Different receptor but same hormone
(See p. 3 in NOTES)
True or False: most target cells are sensitive to multiple hormones.
TRUE
What are the TWO (2) main types of INTERACTIVE EFFECTS of hormones?
Synergistic
Antagonistic
This type of INTERACTIVE EFFECT occurs when TWO HORMONES act to produce GREATER EFFECT.
Synergistic
This type of INTERACTIVE EFFECT occurs when ONE HORMONE OPPOSES the ACTION of another.
Antagonistic
This is the MAJOR FUEL for animals.
Glucose
What are the TWO (2) ANTAGONISTIC hormones?
Insulin
Glucagon
What FUNCTION does INSULIN serve?
LOWERS a blood glucose
What GLAND secretes INSULIN?
Pancreas
What is the FUNCTION of GLUCAGON?
It INCREASES blood glucose
Which GLAND secretes GLUCAGON?
Pancreas
This is the result of a DISRUPTION in GLUCOSE HOMEOSTASIS.
Diabetes Mellitus
Type 1 DIABETES is the result of what?
A DEFICIENCY in insulin PRODUCTION.
Type 2 DIABETES is a result of what?
DEFICIENCY in insulin RECEPTORS on target cells.
90% of cases of DIABETES are type __.
2
This is the MAJOR ENDOCRINE GLAND.
Pituitary
This organ CONTROLS the PITUITARY GLAND.
Hypothalamus
Name the TWO (2) LOBES of the PITUITARY GLAND.
Anterior
Posterior
The ANTERIOR pituitary gland SECRETES ___ hormones.
6
The POSTERIOR pituitary gland SECRETES ___ hormones.
2
Name the SIX (6) HORMONES secretes by the ANTERIOR PITUITARY GLAND.
- ) Growth Hormone (GH)
- ) Prolactin
- ) Follicle-stimulating Hormone (FSH)
- ) Luteinizing Hormone
- ) Thyroid Stimulating Hormone (TSH)
- ) Adrenocorticotropic Hormone (ACTH)
What are the TWO (2) HORMONES secreted by the POSTERIOR PITUITARY GLAND?
- ) Oxytocin
2. ) Antidiuretic Hormone
What role does PROLACTIN of the ANTERIOR PITUITARY GLAND play in the endocrine system?
Milk synthesis and secretion
What role does GROWTH HORMONE of the ANTERIOR PITUITARY GLAND play in the endocrine system?
Growth
Metabolic functions
What role does FOLLICLE-STIMULATING HORMONE of the ANTERIOR PITUITARY GLAND play in the endocrine system?
Ova and Sperm production
What role does LUTEINIZING HORMONE of the ANTERIOR PITUITARY GLAND play in the endocrine system?
Stimulates Ovulation and Estrogen (ovaries) Stimulates Androgens (testes)
What role does THYROID-STIMULATING HORMONE of the ANTERIOR PITUITARY GLAND play in the endocrine system?
Stimulates Thyroid Gland
What role does ADRENOCORTICOTROPIC HORMONE of the ANTERIOR PITUITARY GLAND play in the endocrine system?
Stimulates Adrenal Glands
What role does OXYTOCIN of the POSTERIOR PITUITARY GLAND play in the endocrine system?
Stimulates Mammary Gland Cells
Stimulates Uterus Contraction
What role does ANTIDIURETIC HORMONE of the POSTERIOR PITUITARY GLAND play in the endocrine system?
Promotes H2O Retention by kidneys
The THYROID GLAND consists of ___ large LOBES.
2
The THYROID GLAND is POSITIONED just below the __________.
Larynx
What TWO (2) HORMONES does the THYROID GLAND PRODUCE?
Thyroid Hormone
Calcitonin
What TWO (2) CHEMICALS make up THYROID HORMONE?
Thyroxine
Triiodothyronine
What THREE (3) METABOLIC PROCESSES does THYROID HORMONE influence?
- ) INCREASES ENERGY RELEASE from carbs
- ) INCREASES rate of PROTEIN SYNTHESIS
- ) ACCELERATES GROWTH
This endocrine gland STIMULATES the THYROID GLAND.
Anterior pituitary gland
These TWO (2) COMPLICATIONS arise due to THYROID HORMONE IMBALANCES
Grave’s Disease
Goiter
What is the FUNCTION of CALCITONIN?
Lowers blood calcium levels
How does CALCITONIN lower blood calcium levels?
It INCREASES EXCRETION of calcium in urine.
This is the ANTAGONISTIC hormone to CALCITONIN, in that it INCREASES BLOOD CALCIUM.
Parathyroid Hormone
In what THREE (3) WAYS does PARATHYROID HORMONE INCREASE blood CALCIUM?
- ) Calcium UPTAKE in KIDNEYS
- ) Calcium UPTAKE in INTESTINES
- ) Calcium RELEASE from BONES
What GLAND secretes PARATHYROID HORMONE?
Parathyroid Glands
These GLANDS are located ABOVE the KIDNEYS and divided into 2 LAYERS.
Adrenal Glands
What are the TWO (2) LAYERS a of the ADRENAL GLANDS?
Adrenal Medulla
Adrenal Cortex
The ADRENAL MEDULLA secretes this HORMONE.
Epinephrine
The ADRENAL CORTEX secretes ___ different STEROIDS. Name TWO (2).
30
Glucocorticoids
Mineralcorticosteroids
What is the FUNCTION of EPINEPHRINE?
FIGHT OR FLIGHT:
- ) Increased Heart Rate
- ) Increased Breathing Rate
- ) Increased Metabolic Rate
- ) Decreased Digestion
What is the FUNCTION of GLUCOCORTICOIDS?
RAISE blood GLUCOSE levels (NON-CARB sources)
ANTI-INFLAMMATORY Effects
What is the FUNCTION of MINERALCORTICOSTEROIDS?
Maintain SALT and WATER BALANCE
Promotes SODIUM REABSORPTION in kidneys
Besides MINERALCORTICOSTEROIDS, what is another HORMONE involved in WATER REABSORPTION?
Antidiuretic Hormone (ADH)
What are the TWO (2) ANTAGONISTIC hormones of the PANCREAS?
Insulin
Glucagon
This ANTAGONISTIC hormone LOWERS blood GLUCOSE.
Insulin
This ANTAGONISTIC hormone INCREASES blood GLUCOSE.
Glucagon
GONADS produce what TWO (2) STEROID HORMONES?
Androgens
Estrogens
GONADAL SEX HORMONES are STIMULATED by what other 2 hormones?
Follicle-stimulating
Luteinizing