Endocrine Flashcards

1
Q

PHPTH (primary hyperparathyroidism) diagnosis?

A

PTH (normal) with high iCa

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2
Q

What hormone is produced by the anterior pituitary?

A

Prolactin

Also FSH, LH and TSH, GH, ACTH

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3
Q

What is the fastest acting thyroid hormone?

Which thyroid hormone has the shortest latency until effect?

A

T3 and also T3

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4
Q

What is the effect of somatostatin?

A

Inhibits secretion of glucagon (also insulin and gastrin)

Inhibits growth hormone

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5
Q

What is the effect of PTH on the calcium in the kidneys?

A

Ca resorption

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6
Q

What is a complication/progression of untreated Addison’s?

A

Increased creatinine

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7
Q

What is the most sensitive test for hyperthyroidism?

A

Scintigraphy

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8
Q

What is the most likely diagnosis in a patient that is dehydrated, hypernatremic, hyposthenuric, mildly azotemic, hyporephosphatemic and has decreased osmolality?

A

CDI?

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9
Q

Best treatment for hyperlipidemia and hypertriglyceridemia?

A

Low fat diet

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10
Q

What metabolite may lead to DKA when low?

A

Oxaloacetate

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11
Q

What hormone increases GFR?

A

PGE2

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12
Q

What is an endocrine cause of hypokalemia?

A

Hyperaldosteronism

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13
Q

What does calcitonin do?

A

Opposite effect of parathyroid on calcium and phosphate…

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14
Q

What fluid type would you use in a patient with DKA?

A

Normal saline

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15
Q

What are some prognostic factors for pituitary macroadenoma post radiation?

A

Resolution of neurological signs?

signs of hyperadrenocorticism take a long time to resolve

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16
Q

What is the most common cause of insulin resistance in cats with diabetes?

A

Pancreatitis

An other is acromegaly

17
Q

Giving a PP dog (psychogenic/primary polydypsia) DDAVP leads to what?

A

Hyponatremia

18
Q

What blood change is expected with hyperthyroidism?

A

ALT (elevation?)

19
Q

Dog with a USG of 1.005. Dog fails to respond to water deprivation or vasopressin. What is the diagnosis?

A

Nephrogenic diabetes insipidus

20
Q

What is the most potent stimulator for aldosterone secretion?

A

Elevated K+

21
Q

What is the stimulation for ADH secretion?

A

Osmotic receptors in the supraoptic nuclei.

22
Q

What is the most common cause for migrating necrotizing dermatitis?

A

Glucagonoma

23
Q

Old cat with DKA; given bloodwork showing severe acidosis, mildly low K, very low Cl, severe hyperglycemia, ketonuria/glucosuria; how to treat first

A

Fluid therapy with 0.9% NaCl (vs insulin)

24
Q

Interpret a low dose dexamethasone suppression test that shows no suppression at 4 or 8 hours

A

Consistent with hyperadrenocorticism but cannot tell which type.

25
What is the ideal diet for a cat with diabetes?
High protein, low carb
26
What is the enzyme of the adrenal cortex that is stimulated by ACTH?
Cholesterol desmolase
27
What does hyperthyroidism decrease in order to cause increased glomerular filtration rate?
Total peripheral resistance
28
What is the most sensitive test for hyperthyroidism?
Scintigraphy
29
Enzyme targeted by trilostane
3β-hydroxysteroid dehydrogenase