Endo: Endo-Related Depression

Question 1

Name the 2 manifestations of psychosis.

Does this occur in endocrine or psychiatric disorders?

Answer 1

• Hallucinations (any sensory modality) or delusions
• Can occur in endocrine or psychiatric disorders
  
  • Hypercalcemia can cause psychosis

Question 2

How does T3/4 affect CNS development? (3)

Answer 2

Thyroid hormones (1) are prevalent in the amygdala, and hippocampus and (2) affects catecholamine concentrations

Question 3

What are two demographics susceptible to hypothyroidism?

Answer 3

• Peripartum women (usually transient)
• Older women

Question 4

What lab is abnormal in subclinical hypothyroidism/hyperthyroidism?

Answer 4

• Subclinical thyroid problems are diagnosed by abnormal TSH

Question 5

What is Sheehan’s syndrome?

Name 2 presenting symptoms

Answer 5

• Infarction of pituitary due to post-partum hemorrhage & hypovolemia
• Can present as post-partum depression, inability to lactate

Question 6

Endocrine side effects of atypical antipsychotics (2) and lithium (1)

Answer 6

• Atypical antipsychotics: weight gain, diabetes
• Lithium: hypothyroidism