Embyological Basis Of Head And Neck Flashcards

1
Q

When does the blastocyst implantation occurs.

A

Week 2.

They also form the bilaminar disc (epiblast + hypoblast)

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2
Q

What is gastrulation? And whin does it happen?

A

Formation of endoderm and mesoderm as a result of epiblast migration.
This happen in week 3

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3
Q

Appearance of the branchial (pharyngeal) arches occur during.

A

4-5th week

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4
Q

This arch in human neither never formed or regressed early.

A

5th arch

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5
Q

What does the arch apparatus consist of?

A
  • branchial arches.
  • branchial clefts.
  • branchial membrane.
  • pharyngeal pouches.
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6
Q

The mesencymal core consist of.

A

Mesoderm + Neural crest cells

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7
Q

What is the mesenchymal derivatives of cartilages?

A
  • neural crest cells (1 - 3).

- lateral plate mesoderm (4 and 6)

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8
Q

Develops from paraxial mesoderm.

A

Skeletal muscles

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9
Q

What is the derivative of external acoustic meatus?

A

The 1st branchial cleft

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10
Q

What forms the neck contour?

A

Formed when the 2nd arch overgrow the 3rd and 4th arches

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11
Q

A defect when 2nd arch fails to overgrow the 3rd and 4th completely.

A

Lateral cervical cyst

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12
Q

The 1st branchial membrane gives rise to.

A

Eardrums

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13
Q

1st pouch forms.

A

auditory tube and middle ear.

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14
Q

Pouches are lined by.

A

Endoderm

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15
Q

2nd pouch forms.

A

The palatine tonsils

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16
Q

3rd pouch forms.

A

Thymus lobules (ventral wing) and inferior parathyroid (dorsal wing) glands

17
Q

4th pouch forms.

A

Superior parathyroid (dorsal wing) + parafollicular cells of thyroid (ventral wing) glands

18
Q

Failure of 3rd and 4th pouches to differentiate.

A

DiGeorge syndrome (also small deletion of ch.22)

19
Q

What are the derivatives of cartilage of 2nd pharyngeal arch?

A

The ventral end: the lesser cornu and the upper part of the body of the hyoid bone.
The dorsal end: the stapes, styloid process and stylohyoid ligament

20
Q

What are the 5 facial processes that form by end of week 5?

A
  • unpaired frontonasal process.
  • 2 maxillary processes.
  • 2 mandibular processes.
21
Q

Maxillary and mandibular processes derived from.

A

The 1st arch

22
Q

Dorsum and apex of the nose formed from.

A

Frontonasal process

23
Q

Ectodermal thickenings

A

Nasal placodes

24
Q

What is frontonasal dysplasia?

A

Facial congenital anomaly caused by excess of tissue in frontonasal process. (Widely spaced eyes, broad nose, vertical midline groove)

25
Q

Results from failure of merging of maxillary and nasal processes.

A

Cleft lip

26
Q

Defect suppressing the growth of the hillocks.

A

Microtia

27
Q

Accessory appendages.

A

Auricular appendages

28
Q

Tongue buds form from which arch?

A

1st arch

29
Q

Embryologically, skull consist of.

A
  • neurocranium.

- viscerocranium.

30
Q

Skull base formed from.

A

Fusion of cartilagenous plate

31
Q

Premature closure of skull sutures.

A

Craniosynostosis

32
Q

The cartilagenous viscerocranium derived from.

A

The first and second arch cartilages

33
Q

The maxillary process give raise to.

A

Maxilla - zygoma - squamous temporal

34
Q

What is treacher collins syndrome?

A

Characterized by malar and mandibular hypoplasia, slanting palpebral fissures, malformed ears