Embryology Flashcards

1
Q

Growth

A
  • increase in size:
    - number of cells
    - size of cells
    - amount of ECM
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2
Q

Patterning

A
  • establishing correct orientation of preprogrammed subgroups of cell to each other or to surrounding tissues
  • ex: dermoid growth on cornea
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3
Q

Differentiation

A
  • cell becomes committed to cell lineage
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4
Q

Morphogenesis

A
  • any change in shape of individual cells or tissues
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5
Q

Apoptosis

A
  • programmed cell death, differs from necrosis when cells die and disintegrate
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6
Q

Induction

A
  • fate of cells is determined by interactions with another group of cells
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7
Q

Instructive Induction

A
  • a cell receives signal and follows developmental pathway, without signal the cell would follow a different path
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8
Q

Permissive Induction

A
  • cell already on path, needs additional signal to continue down path
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9
Q

Cleavage

A
  • dividing into multiple cells (half the size)
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10
Q

Blastomere

A
  • first division of zygote produces two of these (daughter cells)
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11
Q

Morula

A
  • repeated division of blastomeres results in many cells in a solid sphere
  • cells continue dividing but morula does not grow in size
  • superficial cells become trophoblast (extra-embryonic membranes)
  • internal cells become inner cell mass (embryo)
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12
Q

Blastocyst

A
  • aka blastula
  • fluid accumulates embryo is now this
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13
Q

Epiblast

A
  • cells become the embryo
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14
Q

Hypoblast

A
  • become extraembryonic membranes
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15
Q

Gastrulation

A
  • process of germ layer formation
  • endoderm forms first from inner cell mass
  • formation of primitive streak which forms notochord
  • at end composed all 3 layers
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16
Q

ectoderm

A
  • outer layer
  • responds to signals from notochord to form the plate and then the tube which will become CNS
  • neural crest cells become PNS
  • develops into neural tissue and epidermis
17
Q

mesoderm

A
  • middle germ layer
  • urogenital, circulatory, musculoskeletal
18
Q

endoderm

A
  • inner layer
  • lining GI and respiratory tract
19
Q

Teratogen

A
  • compounds toxic to fetal development
  • toxins, viruses, events during gestation that can affect development at different stages
  • most susceptible at embryonic development due to development of organs and tissues