embryo Flashcards

:)

1
Q

Neural tube defect which involve herniation of the meninges and spinal cord:

A

meningomyelocele

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2
Q

Bilious vomiting in an infant should be considered diagnostic of:

A

midgut malrotation with volvulus until proven otherwise.

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3
Q

The first branchial arch generates :

A

M “MUSCLES”
Mastication muscles: (teMporalis, Masseter, Medial and lateral pterygoids)
and the Mylohyoid, as well as the tensor veli palatini and tensor tympani

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4
Q

The muscles that elevate the palate and the pharynx are derived from branchial archs:

A

branchial arch 1 (tensor veli palatini), branchial arch 3 (the stylopharyngeus), and branchial arch 4 (levator veli palatini).

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5
Q

Branchial arch 2 gives rise to:

A

“S” MUSCLES

Stapedius, Stylohyoid, and facial expression muscles.

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6
Q

The first branchial cleft gives rise to

A

the external auditory meatus, and the second, third, and fourth clefts are obliterated during development

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7
Q

the _____, _____, and _____ clefts are obliterated during development

A

the second, third, and fourth clefts

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8
Q

The clefts are formed from ___________

A

from ectoderm and could not give rise to muscles, which are derived from mesoderm.

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9
Q

fourth branchial pouch gives rise to the

A

superior parathyroids

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10
Q

Clefts, Arches, and Pouches give rise to

A

ectoderm, mesoderm(+ neural crest), and endoderm, respectively.

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11
Q

Pierre Robin sequence

A

micrognathia, glossoptosis, cleft palate, airway obstruction

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12
Q

Treacher Collins syndrome

A

neural crest dysfunction mandibular hypoplasia, facial abnormalities

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13
Q

Examples of first arch syndromes include

A

Treacher Collins syndrome and Pierre Robin syndrome.

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14
Q

Atrial septal defects (ASDs) usually arise from defects in the____

A

septum secundum

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15
Q

ASDs associated with Down syndrome arise from defects in the ____

A

septum primum

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16
Q

How does ASDs present in PE?

A

allow left-to-right shunting of blood during diastole, increasing pulmonary pressures, and present with fixed, wide splitting of S2

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17
Q

Egg-on-a-string sign, also referred to as egg on its side, refers to the cardiomediastinal silhouette seen in :

A

transposition of the great arteries (TGA). (CXR)

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18
Q

A defect in the process vaginalis is the etiology of:

A

of an indirect hernia,

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19
Q

In gastroschisis, the abdominal content is not covered with peritoneum and is typically located on:

A

to the right of the umbilicus.

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20
Q

The diaphragm derives from four fetal structures:

A

the Septum transversum, the Pleuroperitoneal folds, the Body wall, and the Dorsal mesentery of the esophagus. This can be remembered by the mnemonic “Several Parts Build Diaphragm.”

21
Q

Primary spermatocytes are #chromosomes ( _N, _C )

A

46 (2N, 4C) Diploid

22
Q

2ry spermatocytes are #chromosomes ( _N, _C )

A

46 (1N, 2C) Haploid

23
Q

Spermatide is #chromosomes ( _N, _C )

A

23 (1N, 1C) Haploid

24
Q

dIGEORGE syndrome and Velocardial syndrome differ in

A

that Digeorge has parathyroid defects. Velocardial syndrome only palate, facial, and cardiac defects.

25
Failure of the medial nasal processes to fuse results in
cleft lip.
26
when the lateral palatine processes or the median palatine processes fail to fuse with the nasal septum _____ Results
Cleft palate.
27
______is the most common fetal neoplasm and is usually benign.
A teratoma
28
_____________are the most common extragonadal germ cell tumors in infants and children.
Sacrococcygeal teratomas
29
in 2% of the population the ______ persists and is called Meckel diverticulum.
Vitelline duct
30
At least 95% of males with cystic fibrosis are infertile as a result of the improper development of
the mesonephric (Wolffian) duct system, which most often leads to a defective vas deferens.
31
In 1st Trimester how will you expect | β-hCG and PAPP-A for trisomy 21, 18 and 13?
21: β-hCG ↑, PAPP-A↓ 18: β-hCG ↓, PAPP-A↓ 13: β-hCG ↓, PAPP-A↓
32
``` 2nd trimester in trisomy 21 you will expect AFP β-hCG Estriol Inhibin A ```
AFP ↓ β-hCG ↑ Estriol ↓ Inhibin A ↑
33
pattern of fusion failure that is the most common type of cleft lip.
maxillary and medial nasal prominences.
34
At what stage of meiosis will the oocyte be arrested, assuming it is not fertilized?
metaphase II
35
at week 4, ?? cells arrive to the indifferent gonad an remain dormant until puberty?
primordial germ cells
36
When a boy reaches puberty,, primordial germ cells differentiate into:
type A spermatogonia (stem cells through adult life)
37
some type A spermatogonia differentiate into ??? | and then what happens
type B spermatogonia. type B spermatogonia enters enters meiosis I to form primary spematocytes. 2 2ry spermatocytes 2ry spermatocytes enter meiosis II to form 2 spermatids which undergo spermiogenesis.
38
explain oogenesis
week 4: oogonias in the indifferent gonad. oogonias enter meiosis I to form primary oocytes. all primary oocytes are formed by the 5th month of fetal life. arrested in prophase of meiosis I.
39
what happens with the primary oocytes when a girl reaches puberty ?
each month one becomes unarrested and completes meiosis I to form a Secondary oocyte &polar body. Secondary oocyte becomes arrested in meiosis II at metaphase and is ovulated.
40
where does hematopoiesis starts to occur early in life?
initially in the mesoderm surrounding the yolk sac. (6 weeks) later in fetal liver, spleen, thymus(6 w to 3rd trim) then bone marrow.
41
32 cell stage in known as
morula (made of blastomeres)
42
what happens to the morula as fluid develops?
blastocyst.
43
blastocyst is composed by which 2 cells masses?
inner: embryoblast outer: trophoblast
44
body wall defect? gastroschisis / omphalocele/
gastroschisis
45
extrusion of abdominal contents through abdominal folds...?
gastroschisis (R to the umb)
46
fertilization occures mc in
ampulla of uterine tube
47
implantation occurs mc in
post wall of uterus
48
in ectopic pregnancy, implantation occurr mc in
ampulla of the tube (longest part of the tube)