Ébola Flashcards

1
Q

¿Qué tipo de virus es el Ébola?

A

Filovirus - filamento

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2
Q

Ébola

  • Familia
  • ADN o ARN
  • Envuelto o Desnudo
A
  • Filoviridae
  • ssRNA
  • Envuelto
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3
Q

¿En dónde es endémico la Ébola?

A

África
→DRC, Sudán, Liberia, Sierra Leona y Guinea

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4
Q

¿Cómo se transmite la ébola?

A

Contacto directo
- A través de fluidos, pero no tiene que entrar en contacto con las mucosas
- Objetos contaminados

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5
Q

Tropismo del ébola

A
  • Monocitos
  • Macrófagos
  • Cel. dendríticas
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6
Q

¿Qué lesiones produce la ébola?

A
  • Lesión vascular
  • Necrosis tisular
  • Lesión endotelial
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7
Q

Fuertes inductores de tormenta inflamatoria similar a sepsis

A

Ébola

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8
Q

¿En qué organos puede causar necrosis tisular el ébola?

A
  • Hígado
  • Bazo
  • Ganglios linfáticos
  • Pulmones
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9
Q

Ébola

Fiebre de Marburgo

A

Brotes en Zimbabue y kenia

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10
Q

Ébola - Fiebre Hemorrágica

A
  • Puede haber asintomáticos
  • Flu-like
  • Náusea, vómito, diarrea y exantema
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11
Q

¿Cuál es la mortalidad del Ébola?

A

90%

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12
Q

Virus que producen fiebre hemorrágica viral

A
  • Fiebre amarilla
  • Dengue
  • Ebola (no es arbovirus)
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13
Q

Dx ébola

A
  • BSL 4
  • ELISA y PCR
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14
Q

Tx ébola

A

De soporte

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15
Q

¿El ébola tiene vacuna?

A

Sí, recombinante

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