Dyslipidemia - Management Flashcards
What is the relative risk reduction for each 1mmol/L reduction in LDL?
20-22% risk reduction
For primary prevention: what FRS does not need statin therapy?
low risk (FRS<10)
still need other prevention management likfe lifestyle
What groups of FRS do need statin therapy
intermediate and high
Intermediate 10-19
High 20+
For intermediate FRS patients what conditions must be met to initiate treatment besides FRS 10-19.9
5
Must have FRS 10-19.9
plus one of the following:
* LDL 3.5+
* non-HDL 4.2+
* ApoB 1.05+
* Men 50+ or Women 60+ with one CV risk factor
* presence of risk modifier**
Risk modifiers
- CAC>0
- fam hx premature CAD
- Lp(a) 50+
What is the exception for primary prevention low risk FRS patients to need statins
FRS 5-9.9 with LDL 3.5+ esp with other CV risk modifiers
recall risk modifiers: premature CAD in fam hx, Lp(a) 50+, CAC>0
What do people with FRS<10 sitll benefit from
lowering statins via diet, exercise, smoking cessation
Recall what are low, intermediate, and high risk statin conditions?
Reminder: Statin conditions
* * all ASCVD conditions
* DM
* CKD over 50 y/o
* LDL 5+
* familial hypercholesterolemia
remember all statin conditions get statins regardless of risk level
Low:
* familial hypercholesterolemia
* LDL 5+
Intermediate:
* CKD <50yo
* DM
High
* all ASCVD conditions
What is not recommended to treat statin myalgia?
vitamins, minerals, supplements
What are 3 common side effects of statins?
muscle pain
liver enzyme elevation
GI symptoms
What impact can statins have on blood glucose
can increase but typically benefit outweighs risk
What 3 things can you do to help with muscle pain from statins?
lower dose
change to another statin
every other day or twice week dosing
some statin is better than no statin
