DM- LADA

Question 1

DM-LADA

What is LADA

Answer 1

Latent Autoimmune Diabetes in Adults

Question 2

DM-LADA

How is LADA similar to T1DM

2

Answer 2

often presents in adulthood
autoimmune component

Question 3

DM-LADA

Patho of LADA

Answer 3

immune system attacks beta cells that make insulin- similar to T1 but happens more slowly

also involves genetics and is sometimes triggered by infection

Question 4

DM-LADA

Who does LADA often present in

Answer 4

normal weight adults with strong genetic basis

Question 5

DM-LADA

What is important to ask pts you suspect of having LADA

Answer 5

fam hx of DM and age of dx

Question 6

DM-LADA

What should you test to if you’re suspicious of LADA

Answer 6

C-peptide

Question 7

DM-LADA

What does C-peptide decline indicate

Answer 7

supports DX LADA
marker B cell fx of pancreas
B cell fx slower decline in LADA than T1DM

Question 8

DM-LADA

How does a patient with LADA progress

Answer 8

responds to metformin at first but within 6 months needs insulin

Question 9

DM-LADA

Who should you be suspicous of for LADA

Answer 9

patients dx’d with T2DM of normal weight or whos glucose is tough to control on oral antihyperglycemics

Question 10

DM-LADA

Who should be consulted for LADA patients

Answer 10

endocrinology