Dyslipidemia

Question 1

Leading cause of death in the US?

Answer 1

Cardiovascular Disease (CVD)- associated with high cholesterol and lipids with decreased HDL

Question 2

NCEP ATP III risk determinants for CHD: HDL

Answer 2

Optimal: >60
Borderline High 40-59
High Risk >40

Question 3

NCEP ATP III risk Categories

Answer 3

• Low risk: 0-1 risk factor
• Moderate risk: >2 risks; 10yr risk
• Moderately high risk: 2 risks; 10yr risk 10-20%
• High: CHD or CHD risk equivalents; 10-yr risk >20%

Question 4

T/F: A very high risk patient for CHD has LDL >100. Should you consider drug therapy?

Answer 4

Yes

Question 5

You have a moderate high risk patient with LDL <130, should you start therapy?

Answer 5

It is optional. >130 start therapy.

Question 6

When do you start therapy for moderate risk patient for CHD

Answer 6

LDL >160

Question 7

Low risk patient for CHD. When should you start therapy?

Answer 7

LDL >190

Question 8

High risk patients with high TG or low HDL levels what should you consider?

Answer 8

Fibrate or nicotinic acid

Question 9

Pattern of Dyslipidemia in DMII patients

Answer 9

High trigs, low HDL, Qualitative changes in LDL

Question 10

Patient with diabetes should get their LDL below what

Answer 10

<100 without CVD

Question 11

Fibrate can do what to your trigs and HDl levels

Answer 11

Decrease Trigs, increase HDL

Question 12

Niacin (nicotinic acid) can do what to trigs and HDL levels?

Answer 12

Decrease trigs, increase HDL- can cause flushing

Question 13

Ezetimibe (Zetia) can do what?

Answer 13

Further decrease LDL levels by selectively inhibiting intestinal absorption of cholesterol

Question 14

Bile acid sequestrants may do what

Answer 14

Decrease LDL

Question 15

What is lifestyle changes dont decrease lipid levels? What should you prescribe next

Answer 15

Statin- follow up in 6wk to check labs. No improvement, increase dose