Dyslipidemia Flashcards
Type 1 hyperlipidemia
LPL deficiency or Apo C2
Type 1 accumulation of
Chylomicrons
TG
Cholesterol
Manifestation of type I
Pancreatitis
Type 2 ( a and b)
LDL receptor deficiency
Type 2 accumulation of
LDL buildup
Manifestation of type II
Tendon xanthoma
Corneal arcus
Difference between type II à and b
VLDL also accumulâtes in type IIb
Type III
ApoE deficiency
Type III accumulâtes a
Remnant buildup of chylo and VLDL
Manifestations of type III
Palmar xanthoma
Type IV
VLDL overproduction
Type 4 accumulates
TGs
Type 4 manifestation
Pancreatitis
Type V
Same presentation as type 1+ type 4
Abetalipoproteinemia
Deficiency of apoB48 and apoB100
So no LDL, VLDL, chylomicrons
Autosomal recessive
Decreased fat absorption -> steatorrhea
Decreased lipid soluble vits (A &E)