Bioenergetics Flashcards
Cells use energy for
Motility Pumping of molecules across membrane Maintaining temperature Cell growth and division Secreting molecules Sending signals synthesize or degrade molecules Energy to do work
Metabolism
Sum of all chemical reactions that take place in a cell or organism
Catabolism is exergonic or endergonic
Exergonic oxidation
Anabolism is exergonic or endergonic
Endergonic process
Energy containing nutrients
Carbohydrates
Fats
Proteins
Energy depleted end products
CO2
NH3
H2O
Precursors molecules
Amino acids
Fatty acids
Sugars
Nitrogenous bases
Cell macromolecules
Proteins
Polysaccharides
Lipids
Nucleic acid
Form of energy produced during catabolism
ATP
NADH
MADPH
FADH2
Property of metabolic pathways
Overall irreversible
Separate catabolic and anabolic pathways
Has a first committed step close from equilibrium
Regulation occurring mostly at first committed step which becomes rate limiting step
Compartmentation requiring transport system
Factors affecting enzyme amount
Transcription
Translation
MRNA stability
Protein stability
Factors affecting enzyme activity
Metabolites Active site inhibitors Allosteric modulators ATP/ADP energy status NADH / NAD+ Phosphorylation state
Racemization
Change of stereochemistry at chiral center
Epimerization
Change stereochemistry at one carbon center in molecule with more than one chiral carbon
First law of thermodynamics
Total energy of system with surrounding is constant
Energy is not lost nor gained but transferred