Drugs quiz 1 Flashcards
alginic acid
Alginate
- Management of gastro-oesophageal reflux disease
bendrofumethiazide
thiazide diuretic- Inhibition of Na/Cl co-transporter in distal convoluted tubule
- oedema
- hypertension
Ranitidine
Histamine H2 Antagonists
- Gastro-oesophageal reflux disease
- Dyspepsia (gastritis, indigestions)
- NSAID-associated duodenal ulcer (also prescrived prophalactically)
- Gastric ulcers
Lactulose
Osmotic laxative
- constipation
Bisoprolol
class II antiarrhythmic (potassium rectifier)
- Hypertension
- Angina
- Adjunct in heart failure
Ramipril
ACE Inhibitors (ACEi): Inhibit angiotensin converting enzyme
- Hypertension
- heart failure
- prophylaxis for MI
Alteplase
fibrinolytic
binds to and activate plasmin to plasminogen
- ischaemic stroke
- PE
- MI
Spironolactone
aldosterone antagonist: Compete with aldosterone at mineralocorticoid receptor
- oedema (in CHF)
- heart failure
- resistant hypertension
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Adenosine
unclassified antiarrhythmic
Conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome)
Atropine
Muscarinic antagonist:
- Vagal Bradycardia
Diazepam
anxiolytic : increase GABA activity (inhibitor NT)
- anxiety
- status epilepticus and febrile seizures
- muscle spasm
Cefalexin
cephalosporin: bactericidal and have the same mode of action as other β-lactam antibiotics (such as penicillins), but are less susceptible to β-lactamases. Cephalosporinsdisrupt the synthesis of the peptidoglycan layer forming the bacterial cell wall.
- hospital acquired pneumonia
- UTI and pyelonephritis
Clomifene
anti-oestrogen
- Female infertility due to ovulatory dysfunction
Metformin
biguanides
Betamethasone
corticosteroid
- inflammatory skin conditions e.g. eczema/ psoriasis
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Celecoxib
NSAID
- Pain and inflammation in osteoarthritis/ rheumatoid
Rituximab
B-lymphocyte lytic monoclonal antibody
- RA
- Non-hodjkins lymphoma
Bupivacaine
local anaesthetic
prevents depolarization by bindng to the intracellular portion of sodium channels and blocking sodium ion influx into neurons
Neostigmine
anticholinesterases : inhibition of cholinesterase, icnreasing time of ACh in the synaptic cleft
- myasthenia gravis
Atorvastatin
statin: lipid lowering drug
Inhibit the rate limiting step of the mevalonate pathway (HMG-CoA reductase inhibitors)
- Primary hypercholesterolaemia in patients who have not responded adequately to diet and other appropriate measures
- Primary and secondary prevention of cardiovascular events in patients at high risk of a first cardiovascular event
Aspirin
Antiplatelet Agents: Reduction of TXA2 synthesis by COX-1 inhibition
- secondary prevention of CVD e.g. stroke, TIA
- pain and antipyretic
Amlodipine
calcium channel blocker- inhibition of L-type calcium channel
- hypertension
Warfarin
vitalmin K atnagonist- vitamin epoxide reductase inhibition
Flecainide (1C)
class I antiarrhythmic: Sodium channel blocker
Amiloride
potassium sparing diuretic: blocks ENaC at the luminal surface of renal tubule
digoxin
antiarrhythmic: inhibition of Na/K ATPAse
- AF or flutter
- HF
Vitamin K1
warfarin reversal : Promote production of clotting factors
Naloxone
Opioid receptor antagonists
- Overdosage with opioids
Sodium Valproate
Anti-epileptic: indirect increase in GABA synthesis
All forms of epilepsy
