Drug quiz 4 Flashcards
Lidocaine (1B)
class 1 antiarrythmic- sodium channel blocker
- IV treatment for ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated.
- also a local anaesthetic
Atenolol
unclassified antiarrythmic: Beta adrenoceptor blockers (B blocker)
- angina
- treatment after MI
- with or without antihypertensives
Salbutamol
short acting B2 agonist: β adrenoceptor agonists
- symptomatic relief for asthamtics (may be used prior to exercise)
Cyclizine
Drugs for Nausea and Vomiting: H1 antagonists
Rotigotine
Drugs used in Parkinson’s disease:Dopamine Receptor Agonists
- parkinsons
- restless leg syndrome
Paclitaxel
antimetabolite: Taxane
(Microtubule depolymerisation inhibitor)
- ovarian and breast cancer
Methotrexate
- cancer ( Dihydrofolate reductase inhibitor)
- RA (indirect suppression of adhesion molecules on T-cells and neutrophils?)
Diclofenac
NSAID: Cyclooxygenase inhibitors – differing selectivity for COX-1 and COX-2
-
pain and inflammation
- RA
- POST OP pain
Gliclazide
Sulfonylureas: ATP sensitive potassium channel blocker
- DM
Canagliflozin
flozin LSodium–glucose co-transporter 2 (SGLT-2) inhibitors
- DM
Naproxen
NSAIDL Cyclooxygenase inhibitors – differing selectivity for COX-1 and COX-2
- OA/RA
Infliximab
TNF-**α inhibitors
- Crohns
- RA
Cyclophosphamide
Antiproliferative immunosuppressants
- RA
Nitrofurantoin
UTI antibiotic
Lansoprazole
Proton pump inhibitors
- Gastirtis
- GORD
- H.pylori eradication
Verapamil
Class IV Antiarrythmic: calcium channel blocker
- supraventricular arrhythmias
- angina
- hypertension
Propranolol
Beta adrenoceptor blockers
- arrythmia
- hypertension
- essential tremor
- MI
- angina
*
Glycerol suppository
stimulant laxatives
Enhance gut motility and increase water and electrolyte transfer into the lower gut
Loperamide
anti-motility drug: intestinal u-receptor agonist
- diarrhea
- faecal incontinence
Sotalol
class III antiarrythmic: potassium
- ventricular tachyarrythmias
Furosemide
loop diuretic: Inhibition of Na/K/2Cl co-transporter in the loop of Henle
- oedema e.g. nephrotic syndrome
- resistant hypertension
Doxazosin
Alpha adrenoceptor blockers
- hypertension
- BPH
Lisinopril
ACE inhibitors (ACEi): Inhibit angiotensin converting enzyme
- essential hypertension
- HF
Fondaparinux
Synthetic (heparin) pentasaccharide: Inhibition of active clotting factor Xa
- prophylaxis for VTE e.g. before surgery, immbolisation
- treatment for DVT and PE
Dipyridamole
antiplatelet: Phosphodiesterase inhibitor and inhibition of adenosine reuptake in platelets
* secondary prevention of ischaemic stroke (not associated with AF)
Fenofibrate
antiplatelet agent: fibrate: PPAR-α activator
- Adjunct to diet and other appropriate measures in mixed hyperlipidaemia if statin contraindicated or not tolerated,
Tranexamic acid
Antifibrinolytics: Inhibit the activation of plasminogen from plasmin
- Menorrhagia
- Local fibrinolysis
- Epistaxis
- Prevention and treatment of significant haemorrhage following trauma
Tiotropium bromide
long action anti-muscarinic
- prevent wheezing, shortness of breath, coughing, and chest tightness in patients with chronic obstructive pulmonary disease, such as chronic bronchitis (swelling of the air passages that lead to the lungs) and emphysema
Midazolam
Anxiolytics: Increase GABA activity (inhibitory neurotransmitter)
- seizure
- conscious sedation for procedures
- premedication
- palliative care
