Drug quiz 6

Question 1

Mesalazine

Answer 1

aminosalicylic acid donors in RA as a DMARD

• primarily UC
• RA

Question 2

Etoricoxib

Answer 2

Cyclooxygenase inhibitors – differing selectivity for COX-1 and COX-2

*

Question 3

Medroxyprogesterone acetate

Answer 3

sythentic progestogen

• contraception
  *

Question 4

zoledronic acid

Answer 4

bisphosphnate

• osteoporosis for menopausal women
• Prevention of skeletal related events in advanced malignancies involving bone

Question 5

Dexamethasone

Answer 5

systemic corticosteroid

• Suppression of inflammatory and allergic disorders
• Local treatment of inflammation (short-term)

*

Question 6

Rosiglitazone

Answer 6

PPARγ receptor agonists

• DM

Question 7

Sitagliptin

Answer 7

dipeptidyl peptidase 4 (DPP-4) inhibitor

• dm

Question 8

Doxycycline

Answer 8

tetracycline: inhibits cell wall synthesis

• UTI
• sinusitis
• human bites
• diabetic foot ulcer
  *

Question 9

Flucloxacillin

Answer 9

penicillin: inhibtis cell wall synthesis

Question 10

Entacapone

Answer 10

Catechol-O-methyl transferase (COMT) inhibitors

• parkinsons

Question 11

Ropinirole

Answer 11

Dopamine Receptor Agonists

• parkinsons

Question 12

Lamotrigine

Answer 12

sodium channel blocker

• antiepileptic

Question 13

Diamorphine

Answer 13

Opioid receptor agonists

• acute pain

Question 14

Chlorpromazine

Answer 14

Primarily post synaptic D2 receptor antagonism – can be used as antiemetic agents

• antipsychotic

Question 15

Midazolam

Answer 15

Increase GABA activity (inhibitory neurotransmitter)

• anxiolytic

Question 16

Aprepitant

Answer 16

neurokinin-1 antagonist

• antiemetic which targets the chemoreceptor trigger zone

Question 17

Fentanyl

Answer 17

Opioid receptor agonists

*

Question 18

Terbutaline

Answer 18

M3 receptor antagonists: long acting anti-muscarinic

*

Question 20

Budesonide

Answer 20

inhaled corticosteroid

• asthma

Question 21

Montelukast

Answer 21

Leukotriene Receptor Antagonists

Question 22

Formoterol

Answer 22

long acting B2 agonist

• asthma

Question 23

Prasugrel

Answer 23

ADP (P2Y12) receptor antagonists

• antiplatelet

Question 24

Prothrombin complex concentrate

Answer 24

promote production of clotting factors

• Warfarin reversal

Question 25

Dabigatran

Answer 25

DOAC: Inhibition of active clotting factor IIa (thrombin)

• DVT
• PE

Question 26

Dalteparin

Answer 26

LMWH: Inhibition of active clotting factor Xa

• DVT
• PE
• CAD

Question 27

Labetalol

Answer 27

B adreoreceptor blocker

Question 28

Indapamide

Answer 28

thiazide like diuretic: inhibiting reabsorption of sodium (Na+) and chloride (Cl−) ions from the distal convoluted tubules in the kidneys by blocking the thiazide-sensitive Na+-Cl− symport

• hypertension
• oedema

Question 29

Ispaghula husk,

Answer 29

bulk forming laxative

• Stimulation through increased faecal bulk, hydrophilic action causing gut lumen water retention

Question 30

Senna

Answer 30

stimulant laxative

• Enhance gut motility and increase water and electrolyte transfer into the lower gut