Drugs only Flashcards

1
Q

Has a short half life; is an adenosine receptor antagonist (DECREASE)

A

Caffeine

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2
Q

A precursor to DA (INCREASE)

A

L-DOPA

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3
Q

A precursor to 5-HT (INCREASE)

A

Tryptophan

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4
Q

Inhibits synthesis of DA and NE (DECREASE)

A

Alpha-methyl-para-tyrosine (AMPT)

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5
Q

The enzyme that makes DA and NE

A

tyrosine hydroxylase

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6
Q

Inhibits the synthesis of 5-HT (DECREASE)

A

Para-chlorophenylalanine

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7
Q

The enzyme that makes 5-HT

A

tryptophan hydroxylase

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8
Q

Prevents the packing of DA, 5-HT, NE into vesicles by blocking vesicular transporters (DECREASE)

A

Reserpine

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9
Q

reverses the uptake transporter for DA and NE (INCREASE)

A

d-amphetamine (adderall)

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10
Q

reverses the uptake transporter for NE, but has less BBB permeability (INCREASE)

A

pseudoephedrine (decongestant)

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11
Q

Stops release of ACh from vesicles in neuromucular junction (DECREASE)

A

botulinum toxin (botox)

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12
Q

A 5-HT autoreceptor agonist (DECREASE)

A

8-OH-DPAT

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13
Q

An NE autoreceptor antagonist (INCREASE)

A

yohimbine

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14
Q

blocks MAO (enzyme that breaks down monoamines) (INCREASE)

A

phenelzine

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15
Q

Blocks uptake transporters for DA, 5-HT. NE (INCREASE)

A

cocaine

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16
Q

A neurotoxin for DA

A

6-hydroxydopamine

17
Q

An ACh muscarinic receptor antagonist (decreases parasympathetic activation)

A

atropine

18
Q

NE receptor agonist (INCREASE)

A

clonidine

19
Q

5-HT autoreceptor antagonist (INCREASE)

A

pinodolol

20
Q

blocks acetyl-cholinesterase to block breakdown of Ach (INCREASE)

A

physostigmine

21
Q

block uptake transporters for NE (INCREASE)

A

tricyclic antidepressants