Drugs for Trypanosomes Flashcards

1
Q

Drugs for trypansomes

A
Pentamidine
Melarsoprol
Nifurtimox
Suramin
Eflornithine
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2
Q

Pentamidine

A

Hemolytic stage of infection

No X BBB

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3
Q

Melarsoprol

A

Oganic arsenic that inhibits sulfhydryl groups\

Can X BBB

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4
Q

Nifurtimox

A

Inhibits enzyme unique to trypanosomes - trypanthione reductase

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5
Q

Sumarin

A

DOC for early hemolytic stages

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6
Q

Eflornithine

A

Suicide substrate of ornithine decarboxylase

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