Antidotes Flashcards

1
Q

Acetominophen

A

N acetylcysteine

replenishes glutathione

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2
Q

AChE Inhibitors, organophosphates

A

Atropine with Pralidoxime

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3
Q

Amphetamines (basic)

A

NH4Cl to acidify the urine which draws the drug into the urine

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4
Q

Antimuscarininc / Anticholinergic agents

A

Physostigmine

give a muscarinic or a cholinergic

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5
Q

Benzos

A

Flumazenil

Competes for GABA Cl- channel

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6
Q

B Blockers

A

Glucagon

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7
Q

CO

A

100% O2, hyperbaric O2

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8
Q

Cu / Arsenic / Gold

A

Penicillamine

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9
Q

Cyanide

A

Nitrite + Thiosulfate, Hydroxycobalamin
Nitrite fixes MetHgb
Thiosulfate for endogenous toxicity

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10
Q

Digitalis

A

Anti-dig Fab Fragments

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11
Q

Heparin

A

Protamine sulfate

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12
Q

Iron

A

Deferoxamine (acute), Deferasirox (chronic)

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13
Q

Lead

A

EDTA
Dimercaprol
Succimer
Penicillamine

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14
Q

MERcury, Arsenic, Gold

A

DiMERcaprol (BAL)

Succimer

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15
Q

Methanol, ethylene glycol

A

Fomepizole > ethanol dialysis

compete for ADH receptors

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16
Q

METHemoglobin

A

Methylene blue, Vit C

17
Q

Opiods

A

Naloxone

18
Q

Salicylates

A

NaHCO3 (alkalinize urine)

Dialysis

19
Q

TCAs

A

NaHCO3 (plasma alkalinization)

20
Q

tPA, Streptokinase, urokinase

A

Aminocaproic Acid

21
Q

Warfarin

A

Vit K, plasma if active bleeding

22
Q

Ca2+ channel blockers

A

Ca2+, IV fluids
Atropine
Vasopressors

Btw, low Ca leads to hyperglycemia bc need Ca for insulin release