Antidotes Flashcards
Acetominophen
N acetylcysteine
replenishes glutathione
AChE Inhibitors, organophosphates
Atropine with Pralidoxime
Amphetamines (basic)
NH4Cl to acidify the urine which draws the drug into the urine
Antimuscarininc / Anticholinergic agents
Physostigmine
give a muscarinic or a cholinergic
Benzos
Flumazenil
Competes for GABA Cl- channel
B Blockers
Glucagon
CO
100% O2, hyperbaric O2
Cu / Arsenic / Gold
Penicillamine
Cyanide
Nitrite + Thiosulfate, Hydroxycobalamin
Nitrite fixes MetHgb
Thiosulfate for endogenous toxicity
Digitalis
Anti-dig Fab Fragments
Heparin
Protamine sulfate
Iron
Deferoxamine (acute), Deferasirox (chronic)
Lead
EDTA
Dimercaprol
Succimer
Penicillamine
MERcury, Arsenic, Gold
DiMERcaprol (BAL)
Succimer
Methanol, ethylene glycol
Fomepizole > ethanol dialysis
compete for ADH receptors