Drugs for Pneumocystis / Toxoplasmosis Flashcards
1
Q
What are the drugs for Pneumocystis?
A
Pentamidine
TMP-SMZ
Pyrimethamine and Sulfnonides
Atorvaquone
2
Q
Pentamidine
A
Inhibition of glycolysis or nucleic acid metabolism
can be used for prophylaxis
3
Q
TMP-SMA
A
PROPHYLAXIS FOR PNEUMOCYSTIS esp in AIDS patients with counts below 200
4
Q
Pyrimethamine with Sulfonamides
A
Synergistic action against TOXOPLASMA through sequential blockade of 2 steps of folic acid synthesis
5
Q
Atorvaquone
A
Inhibits mitochondrial e-transport and folate metabolism