Cytochrome P450 Inducers (+)

Question 1

Inducers do what to the metabolism of drugs?

Answer 1

They will cause the liver to metabolize faster so the drugs are gone faster…will find at sub therapeutic levels

Question 2

What are the Inducers?

Answer 2

Chronic Alcoholic Mona STeals Phen-Phen and NEver Refuses GReasy CARBs

Chronic Alcoholism
Modafinil
St. Johns Wort
PHENytoin
PHENobarbital
NEvirapine
Rifampine
GRiseofulvin
Carbamazepine

Question 3

What are the substrates?

Answer 3

Always Always Always Always Think When Starting Others

Anti-epileptics
Antidepressants
Antipsychotics
Anesthetics
Theophylline
Warfarin
Statins
OCPs

Question 4

What are the inhibitors?

Cause the drugs to stay around too long–>OD

Answer 4

A cute Gentleman CIPped Iced GRAPEFRUIT JUICE QUIckly And Kept Munching on Soft Cinammin Rolls

Acute Alcohol Abuse
Gemfibrozil
Cipro
Isoniazid
Grapefruit Juice
Quinidine
Amiodorone
Ketoconizole
Macrolides
Sulfonamides
Cimetidine
Ritonavir