Drugs 5:1-18

Question 1

rabeprazole brand name and uses

Answer 1

• Aciphex
• Erosive esophagitis
• Adjunct H. pylori regimen

Question 2

rabeprazole dosing

Answer 2

• Erosive esophagitis: 20 mg daily; 4-8 week initial treatment; 20 mg daily maintenance
• Adjunct H. pylori regimen: 20 mg bid + Amoxicillin 1000 mg bid + Clarithromycin 500 mg bid; ideally 14 days

Question 3

esomeprazole brand name and uses

Answer 3

• Nexium
• Erosive esophagitis
• Adjunct H. pylori regimen

Question 4

esomeprazole dosing

Answer 4

• Erosive esophagitis: 20-40 mg daily; 4-8 week initial treatment; 20 mg daily maintenance
• Adjunct H. pylori regimen: 40 mg daily + Amoxicillin 1000 mg bid & Clarithromycin 500 mg bid; ideally 14 days

Question 5

lansoprazole brand name and uses

Answer 5

• Prevacid
• Erosive esophagitis
• Adjunct H. pylori regimen

Question 6

lansoprazole dosing

Answer 6

• Erosive esophagitis: 30 mg daily; 8 week initial treatment; 15 mg daily maintenance
• Adjunct H. pylori regimen: 30 mg bid + Amoxicillin 1000 mg bid & Clarithromycin 500 mg bid; ideally 14 days

Question 7

omeprazole brand name and uses

Answer 7

• Prilosec
• Erosive esophagitis
• Adjunct H. pylori regimen

Question 8

omeprazole dosing

Answer 8

• Erosive esophagitis: 20 mg daily; 4-8 week initial treatment; 20 mg daily maintenance
• Adjunct H. pylori regimen: 20 mg bid + Amoxicillin 1000 mg bid & Clarithromycin 500 mg bid; ideally 14 days

Question 9

pantoprazole brand name and uses

Answer 9

• Protonix

- Erosive esophagitis

Question 10

pantoprazole dosing

Answer 10

40 mg daily; 8 week initial treatment; 40 mg daily maintenance; also IV

Question 11

dexlansoprazole brand name and uses

Answer 11

• Dexilant

- Erosive esophagitis

Question 12

dexlansoprazole dosing

Answer 12

60 mg daily; 8 week initial treatment; 30 mg daily maintenance

Question 13

famotidine brand name and uses

Answer 13

• Pepcid
• Duodenal ulcer
• GERD

Question 14

famotidine dosing

Answer 14

• Duodenal ulcer: 20 mg bid or 40 mg qhs; 20 mg qhs maintenance
• GERD: 20-40 mg bid; 6-12 week initial treatment; 20 mg qhs maintenance

Question 15

cimetidine brand name and uses

Answer 15

• Tagamet

- Erosive esophagitis

Question 16

cimetidine dosing

Answer 16

400 mg qid; 12 week initial treatment

Question 17

ranitidine brand name and uses

Answer 17

• Zantac
• Duodenal ulcer
• Erosive esophagitis

Question 18

ranitidine dosing

Answer 18

• Duodenal ulcer: 150 mg bid; 150 mg qhs for maintenance therapy
• Erosive esophagitis: 150 mg qid; 150 bid for maintenance therapy

Question 19

sucralfate brand name and uses

Answer 19

• Carafate

- Duodenal ulcer

Question 20

sucralfate dosing

Answer 20

1 gram qid (before meals and at hs); 4-8 week initial course; 1 gram bid maintenance

Question 21

misoprostol brand name and uses

Answer 21

• Cytotec

- reduce NSAID-induced gastric ulcers

Question 22

misoprostol dosing

Answer 22

200 mcg qid

Question 23

mesalamine brand name and uses

Answer 23

• Asacol HD

- treatment and maintenance of ulcerative colitis

Question 24

mesalamine dosing

Answer 24

• 800 mg tablets

- 2 tabs tid (adult); acute treatment indicated for 6 weeks

Question 25

balsalazide brand name and uses

Answer 25

- Colazal | - treatment of active ulcerative colitis

Question 26

balsalazide dosing

Answer 26

- 750 mg capsules | - 3 capsules tid (adult); acute treatment indicated for 8-12 weeks

Question 27

olsalazine brand name and uses

Answer 27

- Dipentum | - maintenance of ulcerative colitis

Question 28

olsalazine dosing

Answer 28

- 250 mg capsules | - 2 capsules bid (adult)

Question 29

sulfasalazine brand name and uses

Answer 29

- Azulfidine | - treatment and maintenance of ulcerative colitis

Question 30

sulfasalazine dosing

Answer 30

- 2000 - 4000 mg initial treatment, divided at least tid - maintenance 2000 mg divided at least TID - comes in 500mg tablets

Question 31

dicyclomine brand name and uses

Answer 31

- Bentyl | - functional / irritable bowel syndrome

Question 32

dicyclomine dosing

Answer 32

20-40 mg tid - qid; give 30 minutes prior to meals

Question 33

hyoscyamine brand name and uses

Answer 33

- Levsin - Levsin - irritable bowel syndrome

Question 34

hyoscyamine dosing

Answer 34

- Levsin: 0.125 mg tabs/0.125mg SL; 1 - 2 q4h prn; empty stomach prior to meals or prn; MAX of 12 tabs/day - Levsin: 0.375 mg; 1 - 2 q12h

Question 35

chlordiazepoxide / clidinium brand name and uses

Answer 35

- Librax | - irritable bowel syndrome

Question 36

chlordiazepoxide / clidinium dosing

Answer 36

1 - 2 tid - qid; before meals / food +/- at bedtime