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OU Practice Fall 2018 > Drugs 1:23-44 > Flashcards

Drugs 1:23-44 Flashcards

1
Q

dipyridamole / aspirin brand name and uses

A
  • Aggrenox

- CVA prevention with h/o TIA or CVA

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2
Q

dipyridamole / aspirin dosing

A

200/25 mg capsule bid

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3
Q

pentoxifylline brand name and uses

A
  • Trental

- intermittent claudication

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4
Q

pentoxifylline dosing

A
  • 400 mg tid

- 8 week trial to assess effectiveness

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5
Q

cilostazol brand name and uses

A
  • Pletal

- intermittent claudication

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6
Q

cilostazol dosing

A
  • 100 mg bid (unless interactions)

- max 50 mg bid (interactions); 2-12 week trial

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7
Q

warfarin brand name and uses

A
  • Coumadin
  • Afib
  • venous thromboembolism
  • not all inclusive list
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8
Q

warfarin dosing

A
  • 2 - 10 mg daily, but highly variable

- average regimen 4 - 5 mg daily

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9
Q

dabigatran brand name and uses

A
  • Pradaxa
  • DVT/PE prevention / treatment after 5-10 days of parenteral anticoagulant
  • stroke prevention in non-valvular Afib
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10
Q

dabigatran dosing

A
  • 150 mg twice daily

- for stroke prevention in non-valvular Afib -> 75 mg bid for CrCl 15-30 ml/min

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11
Q

rivaroxaban brand name and uses

A
  • Xarelto
  • DVT
  • PE prevention s/p joint replacement
  • DVT/PE treatment
  • stroke prevention in non-valvular Afib
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12
Q

rivaroxaban dosing

A
  • DVT, PE prevention s/p joint replacement: 10 mg daily; avoid use for indication when CrCl < 30 ml/min
  • DVT/PE treatment: 15 mg bid x 21 days, then 20 mg/day with food
  • stroke prevention in non-valvular Afib: 20 mg daily with evening meal; 15 mg if CrCl 15-50 ml/min; avoid < 15 ml/min
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13
Q

apixaban brand name and uses

A
  • Eliquis
  • DVT
  • PE prevention s/p joint replacement
  • DVT/PE treatment
  • stroke prevention in non-valvular Afib
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14
Q

apixaban dosing

A
  • DVT, PE prevention s/p joint replacement: 2.5 mg bid (begin 12-24h post-op); therapy duration: hip -35 days, knee-12 days
  • DVT/PE treatment: 10 mg bid x 7 days, then 5 mg bid; 2.5 mg bid after 6 months, to decrease risk
  • stroke prevention in non-valvular Afib: 5 mg bid
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15
Q

edoxaban brand name and uses

A
  • Savaysa
  • DVT / PE treatment after 5-10 days of parenteral anticoagulant
  • stroke prevention in Afib
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16
Q

edoxaban dosing

A
  • DVT, PE treatment: 60 mg daily (30 mg if < 60 kg);

- stroke prevention in Afib: 60 mg daily; 30 mg if CrCl 15-50; avoid if > 95 ml/min

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17
Q

furosemide brand name and uses

A
  • Lasix

- CHF

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18
Q

furosemide dosing

A
  • 20 - 160 mg split into 1-2x/day

- max oral dose = 600 mg

19
Q

bumetanide brand name and uses

A
  • Bumex

- CHF

20
Q

bumetanide dosing

A
  • 0.5 - 10 mg split into 1-2x/day
21
Q

torsemide brand name and uses

A
  • Demadex
  • CHF
  • HTN
22
Q

torsemide dosing

A
  • CHF: 10 - 200 mg daily

- HTN: 5 - 10 mg daily

23
Q

hydrochlorothiazide uses

A

HTN

24
Q

hydrochlorothiazide dosing

A
  • 12.5 - 50 mg daily

- target regimen = 25-50 mg qam

25
Q

indapamide brand name and uses

A
  • Lozol
  • CHF
  • HTN
26
Q

indapamide dosing

A
  • CHF: 2.5 - 5 mg daily

- HTN: 1.25 - 2.5 mg daily; target regimen 1.25-2.5 mg qam

27
Q

chlorthalidone uses

A

HTN

28
Q

chlorthalidone dosing

A

12.5 - 25 mg daily; target regimen = 12.5-25 mg qam

29
Q

metolazone brand name and uses

A
  • Zaroxolyn

- edema due to CHF/renal dysfunction

30
Q

metolazone dosing

A
  • 2.5 - 20 mg daily

- often used as a 2nd diuretic and/or dosed qod

31
Q

potassium chloride uses

A

treatment and/or prevention of hypokalemia

32
Q

potassium chloride dosing

A

16 - 80 mEq split into 1-2x/day

33
Q

spironolactone brand name and uses

A
  • Aldactone
  • edema (CHF, cirrhosis)
  • HTN
34
Q

spironolactone dosing

A
  • edema (CHF, cirrhosis): 25 - 200 mg daily

- HTN: 50 - 100 mg daily

35
Q

eplerenone brand name and uses

A
  • Inspra
  • CHF post MI
  • HTN
36
Q

eplerenone dosing

A
  • CHF post MI: 25 - 50 mg daily; start 25 mg daily; titrate to 50 mg within 4 weeks
  • HTN: 50 mg daily; titrate to 50 mg bid after 4 weeks prn
37
Q

ivabradine brand name and uses

A
  • Corlanor

- specific patients with CHF and EF < 35% to decrease hospitalizations due to CHF

38
Q

ivabradine dosing

A

2.5-5 mg bid initial; 7.5 mg max

39
Q

triamterene 37.5 mg/HCTZ 25 mg brand name and uses

A
  • Dyazide

- HTN

40
Q

triamterene 37.5 mg/HCTZ 25 dosing

A

1-2 caps daily; use the lowest effective dose

41
Q

triamterene 75 mg/HCTZ 50 mg brand name and uses

A
  • Maxzide

- HTN

42
Q

triamterene 75 mg/HCTZ 50 dosing

A

1 tab daily

43
Q

sacubitril / valsartan brand name and uses

A
  • Entresto

- CHF

44
Q

sacubitril / valsartan dosing

A
  • (sacubitril/valsartan) 24/26, 49/51, 97/103

- twice daily (3 strengths)

OU Practice Fall 2018 (17 decks)

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