Drugs 3:1-19 Flashcards
glimepiride brand name and uses
- Amaryl
- Type 2 diabetes
glimepiride dosing
1 - 8 mg
glipizide brand name and uses
- Glucotrol (XL)
- Type 2 diabetes
glipizide dosing
- 2.5 - 40 mg split into 1-2x/day; titrate q1-2wks; divide dose > 15 mg as bid
- XL: 2.5 - 20 mg qd; titrate q1-2wks
glyburide brand name and uses
- Diabeta / (Micronase)
- Type 2 diabetes
glyburide dosing
- 1.25 - 20 mg split into 1-2x/day
- titrate q1-2wks; divide dose > 10 mg as bid
repaglinide brand name and uses
- Prandin
- Type 2 diabetes
repaglinide dosing
- 0.5 - 4 mg tid
- titrate weekly; take 15 minutes pre-meal (0-30 min); max 16 mg/24hrs
nateglinide brand name and uses
- Starlix
- Type 2 diabetes
nateglinide dosing
- 60 - 120 mg tid
- titrate weekly; take 15 minutes pre-meal (0-30 min)
acarbose brand name and uses
- Precose
- Type 2 diabetes
acarbose dosing
- 25 - 100 mg tid
- titrate q4-8wks; skip if meal is missed; max dose by weight
pioglitazone brand name and uses
- Actos
- Type 2 diabetes
pioglitazone dosing
- 15 - 45 mg
- titrate q3months
rosiglitazone brand name and uses
- Avandia
- Type 2 diabetes
rosiglitazone dosing
- 4 - 8 mg split into 1-2x/day
- titrate q3months
metformin brand name and uses
- Glucophage (XR), Glumetza
- Type 2 diabetes
metformin dosing
- 1000 - 2550 mg split into 2-3x/day; start 500 mg qd; titrate 500 mg qwk or 850 mg every other wk; with food
- XR: 500 - 2000 mg qd; with evening meal; can switch to XR at equal dose
- Glumetza: 1000 - 2000 mg with evening meal
glipizide/metformin brand name and uses
- Metaglip
- Type 2 diabetes
glipizide/metformin dosing
- BID
- titrate q2wks; max 20/2000 mg per 24 hrs
glyburide/metformin brand name and uses
- Glucovance
- Type 2 diabetes
glyburide/metformin dosing
- BID
- titrate q2wks; max 20/2000 mg per 24 hrs
pioglitazone/metformin brand name and uses
- Acto Plus Met
- Type 2 diabetes
pioglitazone/metformin dosing
- BID
- max 45/2550 mg per 24 hrs
sitagliptin brand name and uses
- Januvia
- Type 2 diabetes
sitagliptin dosing
- 100 mg
- dosage adjustment for CrCl < 50 ml/min
saxagliptin brand name and uses
- Onglyza
- Type 2 diabetes
saxagliptin dosing
- 2.5 - 5 mg
- dosage adjustment for CrCl < 50 ml/min or with strong CYP 3A4 inhibitors
linagliptin brand name and uses
- Tradjenta
- Type 2 diabetes
linagliptin dosing
- 5 mg
- no dosage adjustment recommended for renal impairment
alogliptin brand name and uses
- Nesina
- Type 2 diabetes
alogliptin dosing
- 25 mg
- 6.25 mg for CrCl 15 to 29 ml/min , 12.5mg for CrCl 30 to < 60ml/min
canagliflozin brand name and uses
- Invokana
- Type 2 diabetes
canagliflozin dosing
- 100 - 300 mg
- prior to the first meal; lower dose for CrCl < 60 ml/min, avoid if < 45 ml/min
dapagliflozin brand name and uses
- Farxiga
- Type 2 diabetes
dapagliflozin dosing
- 5 - 10 mg
- for CrCl > 60 ml/min; not recommended < 60 ml/min, contraindicated < 30
empagliflozin brand name and uses
- Jardiance
- Type 2 diabetes
empagliflozin dosing
- 10 - 25 mg
- for CrCl > 45 ml/min; not recommended < 45 ml/min, contraindicated < 30