Drugs 3:20-38

Question 1

pramlintide brand name and uses

Answer 1

• Symlin

- Type 1 and 2 diabetes

Question 2

pramlintide dosing

Answer 2

• Type 1: 15 mcg sq up to 60 mcg sq pre-meal; prior to major meals; reduce meal time insulin dosage as instructed
• Type 2: prior to major meals; reduce meal time insulin dosage as instructed

Question 3

exenatide brand name and uses

Answer 3

• Byetta
• Bydureon
• Type 2 diabetes

Question 4

exenatide dosing

Answer 4

• Byetta: 5-10 mcg sq bid; administer before morning and evening meals
• Bydureon: 2 mg sq weekly; administer immediately after reconstitution on same day each wk

Question 5

liraglutide brand name and uses

Answer 5

• Victoza: Type 2 diabetes

- Saxenda: Chronic weight management

Question 6

liraglutide dosing

Answer 6

• Victoza: 0.6 mg sq daily x 1 wk, then 1.2 mg daily; administer at same time each day; 1.8 mg sq once daily max
• Saxenda: 0.6 mg sq daily, up to 3 mg sq daily; titate by 0.6 mg/week to target dose; administer at same time each day

Question 7

lixisenatide brand name and uses

Answer 7

• Adlyxin

- Type 2 diabetes

Question 8

lixisenatide dosing

Answer 8

• 10 mcg sq daily, up to 20 mcg sq daily

Question 9

dulaglutide brand name and uses

Answer 9

• Trulicity

- Type 2 diabetes

Question 10

dulaglutide dosing

Answer 10

• 0.75 mg sq up to 1.5 mg sq weekly

- administer once weekly on the same day without regard to meals

Question 11

semaglutide brand name and uses

Answer 11

• Ozempic

- Type 2 diabetes

Question 12

semaglutide dosing

Answer 12

• 0.25 mg up to 1 mg sq weekly

- double the dose every 4 wks (1 mg max); administer on same day each wk

Question 13

insulin lispro/protamine suspension brand name and uses

Answer 13

• Humalog Mix 75/25,50/50

- Diabetes Mellitus

Question 14

insulin lispro/protamine suspension dosing

Answer 14

• individualized; BID

- administer 0-15 minutes before morning and evening meals

Question 15

insulin lispro brand name and uses

Answer 15

• Humalog

- Diabetes Mellitus

Question 16

insulin lispro dosing

Answer 16

• individualized; premeal

- Kwik pen has 100 and 200 units/ml; administer 0-15 minutes pre-meal

Question 17

regular insulin/isophane suspension brand name and uses

Answer 17

• Humulin 70/30, 50/50

- Diabetes Mellitus

Question 18

regular insulin/isophane suspension dosing

Answer 18

• individualized; BID

- administer 30 minutes before morning and evening meals

Question 19

isophane insulin suspension brand name and uses

Answer 19

• Humulin N

- Diabetes Mellitus

Question 20

isophane insulin suspension dosing

Answer 20

• individualized; QD or BID

- intermediate acting

Question 21

regular human insulin brand name and uses

Answer 21

• Humulin R

- Diabetes Mellitus

Question 22

regular human insulin dosing

Answer 22

• individualized; premeal

- administer 30 minutes pre-meal

Question 23

insulin glargine (U-100) brand name and uses

Answer 23

• Lantus / Basaglar

- Diabetes Mellitus

Question 24

insulin glargine (U-100) dosing

Answer 24

• individualized; QD

- reduce total dose by 20% if transferring from NPH bid; 1:1 TO Toujeo

Question 25

insulin glargine (U-300) brand name and uses

Answer 25

- Toujeo/Toujeo Max Solostar | - Diabetes Mellitus

Question 26

insulin glargine (U-300) dosing

Answer 26

- individualized; QD | - reduce total dose by 20% if transferring from NPH bid or TO Lantus

Question 27

insulin detemir brand name and uses

Answer 27

- Levemir | - Diabetes Mellitus

Question 28

insulin detemir dosing

Answer 28

- individualized; QD or BID | - can transfer from another basal insulin on a per unit basis

Question 29

insulin degludec (U-100, U-200) brand name and uses

Answer 29

- Tresiba Flextouch | - Diabetes Mellitus

Question 30

insulin degludec (U-100, U-200) dosing

Answer 30

- individualized; QD | - can transfer from another basal insulin on a per unit basis

Question 31

insulin aspart brand name and uses

Answer 31

- Novolog | - Diabetes Mellitus

Question 32

insulin aspart dosing

Answer 32

- individualized; premeal | - administer 0-15 minutes pre-meal

Question 33

insulin aspart/protamine suspension brand name and uses

Answer 33

- Novolog Mix 70/30 | - Diabetes Mellitus

Question 34

insulin aspart/protamine suspension dosing

Answer 34

- individualized; BID | - administer 0-15 minutes before morning and evening meals

Question 35

insulin glulisine brand name and uses

Answer 35

- Apidra | - Diabetes Mellitus

Question 36

insulin glulisine dosing

Answer 36

- individualized; premeal | - administer 0-15 minutes pre-meal

Question 37

regular human insulin (inhaled) brand name and uses

Answer 37

- Afrezza | - Diabetes Mellitus

Question 38

regular human insulin (inhaled) dosing

Answer 38

- individualized; premeal | - guidelines available for converting from rapid injectable insulin