Drug-Induced Lupus Flashcards
1
Q
does DIL present the same way as SLE?
A
not all the same features - renal and nervous system involvement is unusual
usually resolves on stopping drug
2
Q
features of DIL?
A
arthralgia
myalgia
skin (e.g. malar rash)
pulmonary (e.g. pleurisy)
3
Q
ab a/w DIL?
A
ANA - 100%
anti-histone - 80-90%
5%: anti-Ro, anti-Smith
NOT: dsDNA
4
Q
drugs implicated in DIL?
A
MOST COMMON
procainamide
hydralazine
LESS COMMON
isoniazid
minocycline
phenytoin
