DRUG-DRUG INTERACTIONS

Question 1

Some drug-drug interactions are intended and beneficial others are

Answer 1

Unintended and detrimental

Question 2

May result in intensified effects, diminished effects or an entirely new effect

Answer 2

Drug-drug interactions

Question 3

Beneficial when they increase therapeutic effects and detrimental when the increase adverse effects

Answer 3

Synergistic interactions

Question 4

Beneficial when they decrease adverse effects and detrimental when they decrease beneficial effects

Answer 4

Inhibitory interactions

Question 5

Can result in increased or decreased absorption

Answer 5

Drug interactions

Question 6

Rarely results in a sustained or significant increase in plasma levels of free drug

Answer 6

Competition for protein binding

Question 7

Can accelerate the metabolism of other drugs

Answer 7

Drugs that induce hepatic drug metabolizing enzymes

Question 8

It may be necessary to increase the dosages of other drugs when

Answer 8

an inducing agent that is added to the regime

Question 9

Dosages of other drugs may need to be reduced when

Answer 9

In inducing agent is discontinued

Question 10

A drug that inhibits the metabolism of other drugs will increase their_____.

The result may be beneficial but usually it is_____

Answer 10

Levels

Detrimental

Question 11

We’ll diminish the effects of drugs that act as agonists at that receptor

Answer 11

Drugs that act as antagonists

Question 12

If the antagonist prevents toxic effects of the agonist the result is_____

Answer 12

Beneficial

Question 13

If the antagonist prevents therapeutic effects of the agonist the result is

Answer 13

Detrimental

Question 14

If at all possible, drugs that are toxic to the same organ should not be

Answer 14

Combined

Question 15

By minimizing the number of drugs the patient is given and by taking a thorough history

Answer 15

We can help reduce the risk of adverse interactions