Droperidol

Question 1

Droperidol
Type

Answer 1

Antipsychotic

Question 2

Droperidol
Presentation

Answer 2

10mg in 2ml - vial

Question 3

Droperidol
Actions

Answer 3

Droperidol is an antipyschotic and a tranquiliser. It gives no analgesia and no amnestic effects.
Acts on several neurotransmitters: antipsychotic actions are thought to be mediated by dopamine blockade.
Onset of action: IM 3-10mins; peak action up to 30min; durations 2-4hrs

Question 4

Droperidol
Uses

Answer 4

Pharmacological intervention for combative/agitated patients.

Question 5

Droperidol
Adverse Effects

Answer 5

MEAN
1. May lower seizure threshold
2. Extrapyramidal effects (rare)
3. Arrhythmias, including prolonged QT interval or torsades do pointes (all patients receiving droperidol must have ECG monitoring)
4. Neuroleptic malignant syndrome (rare)

Question 6

Droperidol
Contraindications

Answer 6

1. Known hypersensitivity
2. Parkinson’s disease
3. Post ictal

Question 7

Droperidol
Precautions

Answer 7

Patients in severe pain, analgesia should also be provided

Question 8

Droperidol
Dose

Answer 8

Adult (>14years):
10mg via IM injection only (no IV/IO use) Repeat once, after 10-15mins, if
required

Frail/elderly (>65years):
5mg via IM injection only (no IV/IO use). Repeat once, after 10-15mins, if required