Downing Cells Female Test 2 Flashcards

1
Q

Estrogen Producing Cells

A

Theca cells ad granulosa cells

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2
Q

Progesterone producing cells

A

Corpus luteum

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3
Q

OoGenesis progression

A

Oogonia, primary oocyte, secondary oocyte

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4
Q

Oogonia

A

46 chromosomes, original egg cell prior to birth

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5
Q

Primary Oocyte

A

46 chromosomes, are the eggs at birth, Arrested in Prophase I

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6
Q

Secondary Oocyte

A

23 Chromosomes, Arrested at Metaphase II, are the egg maturing and released at ovulation. 1 polar body produced to create secondary oocyte

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7
Q

Ova

A

Once fertilized, the secondary Oocyte rapidly divides producing another polar body.

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8
Q

Follicular Cells

A

Singer layer of flattened cells surrounding the primordial follicles, contain FSH receptors.

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9
Q

Primary Follicles

A

20-50 respond each menstrual cycle, surround primary oocyte. one follicle becomes dominant and rest undergo atresia

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10
Q

Secondary Follicles

A

begins to form antral space, primar oocyte. contains Theca folliculi

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11
Q

Theca interna

A

highly vascular theca falliculi layer of secondary follicle responsible for androgen production

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12
Q

Theca Externa

A

Fusiform cells and collagen, no known function

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13
Q

Mature follicles

A

LH surge signals final maturation, resumption of meiosis, primary oocyte becomes secondary and is arrested at metaphase II until fertilization. LH surge leads to ovulation and rupture of follicle.

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14
Q

FSH function

A

Granulosa cell growth and estrogen synthesis, Estrogen stimulates increase in LH receptors

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15
Q

LH

A

Stimulates thecal cell growth and androgen production, granulosa cells convert androgens to estrogens

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16
Q

Corpus luteum

A

Temporary glandular structure, thecal lutein cells secrete progesterone. If pregnancy occurrs, it is maintained by HCG, persists during first trimester.

17
Q

Estrogen

A

Produced by growing follicles, induces maturation of female reproductive tract, incluences growth of mamary glands in pregnancy

18
Q

Progesterone

A

Produced by the corpus luteum, causes uterus to secrete layer for endometrial lining, prepares uterus for implantation of fertilized ovum, inhibits uterine contractions

19
Q

Relaxin

A

Produced by corpus luteum and decidual cells., inhibits contraction of myometrium during pregnancy, dilates cervix,

20
Q

Inhibin

A

Produces follicular fluid, negative feedback on FSH production

21
Q

Basal layer of endometrium

A

Responsible for regenerating functional layer of endometrium

22
Q

Blood supply to endometrium

A

one to basal layer, one to endometrium

23
Q

Proliferative phase

A

Begins at end of menstrual flow days 7-14, induced by estrogen, 2-3x increase in endometrial thickness, numerous mitoses in glands and stroma, coiled arteries elongate but do not reach superficial endometrium

24
Q

Secretory Phase

A

days 15-26 ovulation precipitates corpus luteum formation, Increase in progesterone and then estrogen, endometrial thickening
coiled arteries elongate preparing for conceptus

25
Q

Premenstrual phase

A

days 27-28, coiled arteries constrict, corpus luteum regresses, coiled arteries periodically constrict and then permanently constrict at day 28, endometrial detachement begins

26
Q

menstrual phase

A

functional layer of endometriumm undergoes complete necrosis and is shed, venous seepage, clots- RBC aggregates

27
Q

Cervical mucosa

A

not shed with menses, composed of columnar epithelium, produces mucus