Downing Cells Female Test 2 Flashcards
Estrogen Producing Cells
Theca cells ad granulosa cells
Progesterone producing cells
Corpus luteum
OoGenesis progression
Oogonia, primary oocyte, secondary oocyte
Oogonia
46 chromosomes, original egg cell prior to birth
Primary Oocyte
46 chromosomes, are the eggs at birth, Arrested in Prophase I
Secondary Oocyte
23 Chromosomes, Arrested at Metaphase II, are the egg maturing and released at ovulation. 1 polar body produced to create secondary oocyte
Ova
Once fertilized, the secondary Oocyte rapidly divides producing another polar body.
Follicular Cells
Singer layer of flattened cells surrounding the primordial follicles, contain FSH receptors.
Primary Follicles
20-50 respond each menstrual cycle, surround primary oocyte. one follicle becomes dominant and rest undergo atresia
Secondary Follicles
begins to form antral space, primar oocyte. contains Theca folliculi
Theca interna
highly vascular theca falliculi layer of secondary follicle responsible for androgen production
Theca Externa
Fusiform cells and collagen, no known function
Mature follicles
LH surge signals final maturation, resumption of meiosis, primary oocyte becomes secondary and is arrested at metaphase II until fertilization. LH surge leads to ovulation and rupture of follicle.
FSH function
Granulosa cell growth and estrogen synthesis, Estrogen stimulates increase in LH receptors
LH
Stimulates thecal cell growth and androgen production, granulosa cells convert androgens to estrogens