Contraceptives Flashcards
Calender method
avoid sex 5 days prior and 3 days after ovulation
Best STI protection
Condoms
Estrogen/ Progesterone
Inhibiton of midcycle surge of GnRH preventign ovulation
drospirenone
(yaz) spironolactone analog, antimineralocorticoid and antiandrogenic effects
increased K and thromboembolic risk
Norethindrone
least androgenic 1/2 generation progestin. slight improvement in lipid profile
Levonorgestrel
Most widely prescribed progesterone. 2nd generation
Norgestimate
3rd gen progestin, less androgenic effect, good choice for individuals with dyslipidemia, acne, but higher thromboembolic potential
Desogrestrel
3rd gen progestin, less androgenic effect, good choice for individuals with dyslipidemia, acne, but higher thromboembolic potential
Dienogest
Monophasic progesterone combined with estrogen, 3 weeks on, 3 week placebo. Can do extended cycle or no periods
Early bleeding days1-10
increase estrogen
Later bleeding > day 10
increase progesterone
Nuva Ring
ethinyl estradiol and etonogestrel inserted for 3 weeks, removed for one. Plastic
Transdermal Patch
ethinyl estradiol and norelgestromin. once patch a week for 3 weeks, then one week off. good efficacy, greater failure rate in women .90 Kg
Estrogen contraceptives AE
deminish milk supply, increased chance of thromboembolism, endometrial cancer,
Progesterone only Contraceptives
“mini pill” Inhibit ovulation, causes changes in cervical mucous, decreased sperm motility, used while breast feeding, AE: irregular bleeding, androgenicity, need regular dosing, breakthrough ovulation with missed dose. no risk of MI, stroke, endometrial cancer etc.