DNA Replication

Question 1

Name the 4 enzymes involved in replication.

Answer 1

1) Polymerase
2) Helicase
3) Primase
4) Ligase

Question 2

The unzipper?
The builder?
The initializer?
The gluer?

Answer 2

1) Helicase
2) Polymerase
3) Primase
4) Ligase

Question 3

Where does DNA replication begin?

Answer 3

The origin.

Question 4

What does helicase do?

Answer 4

Breaks the hydrogen bond between the two polynucleotide DNA strands.

Question 5

What does primase do?

Answer 5

Primase is an enzyme that synthesizes short RNA sequences called primers. These primers serve as a starting point for DNA synthesis.

Question 6

What does ligase do?

Answer 6

Fills in the gaps between Okazaki fragments.

Question 7

What does polymerase do?

Answer 7

Adds matching nucleotides onto the new strand using base-pairing interactions.

Question 8

What is the replication of DNA known as and why?

Answer 8

Semi-conservative because the new DNA molecule contains the original strand.

Question 9

What are random, spontaneous changes to the DNA base sequence called?

What can the effect on a protein be?

Answer 9

Mutation.

Alteration of the sequence of amino acids. The abnormal protein might function better than the normal protein, or not at all.

Question 10

What is a key feature of the double-helix and its strands?

Answer 10

The strands are antiparallel.