DNA replication Flashcards
What is DNA a polymer of?
Nucleotides
Does circular DNA carry more or less genes?
Less
In terms of DNA in the nucleus, what doesn’t it code for?
Amino acids
What is a gene?
A base sequence (length) of DNA that codes for the amino acid sequence of a polypeptide chain
How could a change in a base sequence effect an enzyme?
- could alter triplet
- Meaning amino acid sequence would be changed (polypeptide chain)
- Would effect the primary structure
- Cause change in tertiary structure and shape of active site of enzyme
- Enzyme-substrate complex unable to be formed
- Enzyme is non functional
Why does a mutation not always effect proteins?
degenerate nature of genetic code, most a/a coded for by more than one triplet
What is the role of histones?
Fix the DNA into position
What bond holds together amino acids?
Polypeptide bonds
What bonds does DNA helicase break?
H bonds
What are H bonds reformed by in transcription?
RNA polymerase
What is an allele/where does it occur?
An alternative form of a gene that that occurs at the same locus on homologous chromosomes