DNA: Nucleotides Flashcards

0
Q

Are responsible for the storage and passage of the information needed for the production of proteins

A

Nucleic acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Are the monomeric units that make up the nucleic acids DNA and RNA

A

Nucleotides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Each nucleotide contains of a

A

Pentose sugar, Nitrogenous base & Phosphate group “PNP”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Result from linking one or more phosphates with a nucleoside onto the 5’ end of the molecule through _________.

A

Nucleotides. Esterification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Is a 5 carbon sugar in a pentose ring form

A

Pentose sugar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

RNA contains ________, which has a hydroxyl group in both the 2’ and 3’ positions.

A

Ribose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Refers to the carbon of the sugar

A

Prime

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Has only a single hydroxyl group in the 3’ position

A

DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A nitrogenous base is attached by a __________ to the 1’ carbon of the nucleotide’s sugar.

A

Glycosylic bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Consist of linked 5-membered and 6-membered rings w/c can be found in DNA or RNA. _______ and _______.

A

Purines. Adenine & Guanine and A & G.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Consists of 6-membered rings. ________, _______ & _______.

A

Pyrimidines. Cytosine, Thymine and Uracil “CTU”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cytosine is found in

A

DNA & RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Thymine is found where

A

DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Uracil is found where

A

RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Are planar, aromatic and heterolytic. Derived from _______ & ______. Numbering of bases is unprimed.

A

Nitrogenous bases. Purine & Pyrimidine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In nitrogenous base, the sugar is linked via ______ to the ___ of pyrimidines and ___ of purines.

A

B-N-glycosylic bond. N-1. N-9.

16
Q

De novo synthesis proceeds via

A

Triphosphate intermediates

17
Q

Purine nucleosides end in

A

Sine

18
Q

Pyrimidine nucleosides end in

A

Dine

19
Q

Nucleotides are linked together by ________ between the __ hydroxyl on the sugar of one nucleotide through a ________ to the __ hydroxyl on the sugar of another nucleotide. These bonds are broken by _________.

A

Phosphodiester bonds. 3’. Phosphate molecule. 5’. Phosphodiesterases.

20
Q

High group transfer potential of __________ permits them to function as group transfer agent (give x)

A

Nucleoside Triphosphates

21
Q

For synthesis of cyclic AMP and cyclic GMP ( a second messenger in response to nitric oxide during smooth muscle relaxation) and fro methyl group transfer (SAM)

A

Nucleotides

22
Q

Participate in the epimerization of sugars for glycogen synthesis, bilirubin synthesis, and phosphoglyceride synthesis.

A

UPD sugars

23
Q

Absorb UV lights

A

Nucleotides

24
Q

are used as antivirals and in cancer chemotherapy

A

Synthetic nucleotide analogues